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Scrib Gene Detail
 Symbol
Name
ID
Scrib
scribbled homolog (Drosophila)
MGI:2145950

Nomenclature History
Synonyms Crc, mKIAA0147, Scrb1
Genetic Map
Chromosome 15
43.8 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 2)

Sequence Map
Chr15:75877588-75900214 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Scrib ± 2 cM)
TreeFam: TF351429
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000021033 VEGA Gene Model | MGI Sequence Detail 22627 C57BL/6J ± Kb
transcript NM_134089 RefSeq | MGI Sequence Detail 5547 C57BL/6
polypeptide Q80U72 UniProt | EBI | MGI Sequence Detail 1612 Not Applicable
For the selected sequences
All sequences(26)
Alleles
and
phenotypes 		All alleles(6) : Gene trapped(4) Spontaneous(1) Chemically induced(1)
Polymorphisms SNPs within 2kb(71 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(18)
Process asymmetric protein localization, cell differentiation...
Component basolateral plasma membrane, cell junction...
Function protein binding
External Resources: MouseFunc
Expression Literature Summary: (7 records)
cDNA source data(138)
External Resources: Allen Brain Atlas  GENSAT  GEO 
Molecular
reagents 		All nucleic(138) cDNA(138)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000022568
DoTS DT.101167471, DT.491121, DT.94272820, DT.99857416
UniGene 25568
DFCI TC1575654, TC1590027, TC1706281
NIA Mouse Gene Index U036324
Entrez Gene 105782
VEGA Gene Model OTTMUSG00000021033
International Mouse Knockout Project Status Scrib
Protein
domains
InterPro ID Description
IPR001478 PDZ/DHR/GLGF
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
Graphical View of Protein Domain Structure
References
(Earliest) J:62635 Rachel RA et al., "Retinal axon misrouting at the optic chiasm in mice with neural tube closure defects." Genesis 2000 May;27(1):32-47
(Latest) J:153473 Sun Y et al., "Scribble interacts with beta-catenin to localize synaptic vesicles to synapses." Mol Biol Cell 2009 Jul;20(14):3390-400
All references(21)
Other
accession IDs 		MGI:1859564
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/20/2009
MGI_4.31
Web browser compatibility 		The Jackson Laboratory