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Fzd10 Gene Detail
 Symbol
Name
ID
Fzd10
frizzled homolog 10 (Drosophila)
MGI:2136761

Nomenclature History
Synonyms Fz-10
Genetic Map
Chromosome 5
Syntenic
 
Mapping data( 2)
Sequence Map
Chr5:129106719-129109968 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic    (Mammalian Orthology)
Protein SuperFamily: G protein-coupled receptor frizzled
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000027707 VEGA Gene Model | MGI Sequence Detail 3250 C57BL/6J ± Kb
transcript NM_175284 RefSeq | MGI Sequence Detail 3005 CD-1
polypeptide Q8BKG4 UniProt | EBI | MGI Sequence Detail 582 Not Applicable
For the selected sequences
All sequences(18)
Alleles
and
phenotypes 		All alleles(1) : Targeted, other(1)
Homozygous mutation of this gene does not appear to result in a phenotype.
Polymorphisms SNPs within 2kb(7 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway...
Component integral to membrane, membrane...
Function G-protein coupled receptor activity, non-G-protein coupled 7TM receptor activity...
External Resources: FuncBase
Expression Literature Summary: (17 records)
Data Summary: Assays (8)    Results (275)    Tissues (215)    Images (92)
Theiler Stages: 1,2,3,4,5,13,15,17,20,22,23,24,25,28
  Assay Type Assays   Results
      RT-PCR 4   57
      In situ reporter (knock in) 1   60
      RNA in situ 3   158
cDNA source data(10)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(16) cDNA(10) Primer pair(6)
Microarray probesets(1)
Other database
links
Ensembl Gene Model ENSMUSG00000054709, ENSMUSG00000081683
DoTS DT.101260357
UniGene 197628
DFCI TC1586435
NIA Mouse Gene Index U006219
Entrez Gene 93897
VEGA Gene Model OTTMUSG00000027707
International Mouse Knockout Project Status Fzd10
Protein
domains
InterPro ID Description
IPR000024 Frizzled cysteine-rich domain
IPR000539 Frizzled protein
IPR015526 Frizzled related
IPR017981 GPCR, family 2-like
IPR020067 Frizzled-like domain
IPR020068 Frizzled domain, subgroup
Graphical View of Protein Domain Structure
References
(Earliest) J:69787 Kim AS et al., "Wnt receptors and Wnt inhibitors are expressed in gradients in the developing telencephalon." Mech Dev 2001 May;103(1-2):167-72
(Latest) J:154363 Bluske KK et al., "Differential activity of Wnt/beta-catenin signaling in the embryonic mouse thalamus." Dev Dyn 2009 Nov 18;238(12):3297-3309
All references(19)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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