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Echs1 Gene Detail
 Symbol
Name
ID
Echs1
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial
MGI:2136460

Nomenclature History
Genetic Map
Chromosome 7
Syntenic
 
Mapping data( 2)
Sequence Map
Chr7:147291609-147302375 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: AU-specific RNA-binding protein AUH
TreeFam: TF314497
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000027297 VEGA Gene Model | MGI Sequence Detail 10767 C57BL/6J ± Kb
transcript NM_053119 RefSeq | MGI Sequence Detail 1491 C57BL/6
polypeptide Q8BH95 UniProt | EBI | MGI Sequence Detail 290 Not Applicable
For the selected sequences
All sequences(29)
Alleles
and
phenotypes 		All alleles(3) : Targeted, other(1) Gene trapped(2)
Polymorphisms SNPs within 2kb(32 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process fatty acid metabolic process, lipid metabolic process...
Component mitochondrion
Function catalytic activity, enoyl-CoA hydratase activity...
External Resources: FuncBase
Expression cDNA source data(175)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(177) cDNA(176) Primer pair(1)
Microarray probesets(2)
Pathways
fatty acid β-oxidation I
very long chain fatty acid biosynthesis
2-methylbutyrate biosynthesis
fatty acid β-oxidation II (core pathway)
fatty acid β-oxidation IV (unsaturated, even number)
glutaryl-CoA degradation
3-hydroxypropionate cycle
3-hydroxypropionate/4-hydroxybutyrate cycle
isoleucine degradation
valine degradation
tryptophan degradation III (eukaryotic)
Other database
links
EC 4.2.1.17
Ensembl Gene Model ENSMUSG00000025465
DoTS DT.101720489, DT.91382465, DT.99848528
Consensus CDS Project CCDS21964.1
UniGene 24452
DFCI TC1572155, TC1698529
NIA Mouse Gene Index U029420
Entrez Gene 93747
VEGA Gene Model OTTMUSG00000027297
International Mouse Knockout Project Status Echs1
Protein
domains
InterPro ID Description
IPR001753 Crotonase, core
IPR018376 Enoyl-CoA hydratase/isomerase, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:60984 Ko MS et al., "Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development." Development 2000 Apr;127(8):1737-49
(Latest) J:151002 Pagliarini DJ et al., "A mitochondrial protein compendium elucidates complex I disease biology." Cell 2008 Jul 11;134(1):112-23
All references(8)
Other
accession IDs 		MGI:2142345
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory