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Vangl2 Gene Detail
 Symbol
Name
ID
Vangl2
vang-like 2 (van gogh, Drosophila)
MGI:2135272


Nomenclature History
Synonyms C530001F03Rik, Lpp1, Ltap, mKIAA1215, strabismus
Genetic Map
Chromosome 1
93.4 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 31)

Sequence Map
Chr1:173931091-173958575 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; cattle; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Vangl2 ± 2 cM)
Protein SuperFamily: Vang-like protein
TreeFam: TF313467
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000021582 VEGA Gene Model | MGI Sequence Detail 27485 C57BL/6J ± Kb
transcript NM_033509 RefSeq | MGI Sequence Detail 2260 C57BL/6
polypeptide Q91ZD4 UniProt | EBI | MGI Sequence Detail 521 Not Applicable
For the selected sequences
All sequences(27)
Alleles
and
phenotypes
All alleles(4) : Gene trapped(2) Spontaneous(1) Chemically induced(1)
Associated Human Diseases (1)   Alleles Annotated to Human Diseases (1)   Phenotype Images (4)  
Polymorphisms SNPs within 2kb(97 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(15)
Process apical protein localization, establishment of planar polarity...
Component apical plasma membrane, integral to membrane...
Function protein binding
External Resources: MouseFunc
Expression Literature Summary: (24 records)
Data Summary: Assays (2)    Results (8)    Tissues (5)    Images (1)
Theiler Stages: 13,15,17,28
  Assay Type Assays   Results
      RT-PCR 1   7
      RNA in situ 1   1
cDNA source data(3)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(8) Genomic(2) cDNA(5) Primer pair(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000026556
DoTS DT.101364832, DT.40179442, DT.97358585, DT.99851998
DFCI TC1581684, TC1604720, TC1604915, TC1615066, TC1650205
NIA Mouse Gene Index U088869, U201395
Entrez Gene 93840
VEGA Gene Model OTTMUSG00000021582
International Mouse Knockout Project Status Vangl2
Protein
domains
InterPro ID Description
IPR009539 Strabismus
Graphical View of Protein Domain Structure
References
(Earliest) J:13059 Strong LC et al., "Hereditary loop-tail in the house mouse accompanied by imperforate vagina and craniorachischisis when homozygous." J Hered 1949;40():329-334
(Latest) J:152701 Suriben R et al., "Posterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streak." Nat Genet 2009 Sep;41(9):977-85
All references(92)
Other
accession IDs
MGD-MRK-11867, MGI:1924856, MGI:96818

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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