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Csnk1a1 Gene Detail
 Symbol
Name
ID
Csnk1a1
casein kinase 1, alpha 1
MGI:1934950

Nomenclature History
Synonyms 2610208K14Rik, 4632404G05Rik, 5430427P18Rik
Genetic Map
Chromosome 18
cytoband D3
 
Mapping data( 2)
Sequence Map
Chr18:61715236-61747953 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rabbit, European; rat; sheep    (Mammalian Orthology)
Protein SuperFamily: kinase-related transforming protein
TreeFam: TF354246
Sequences
Representative Sequences Length Strain/Species Flank
genomic 93687 NCBI Gene Model | MGI Sequence Detail 32718 C57BL/6J ± Kb
transcript NM_146087 RefSeq | MGI Sequence Detail 2013 C57BL/6
polypeptide Q8BK63 UniProt | EBI | MGI Sequence Detail 337 Not Applicable
For the selected sequences
All sequences(75)
Alleles
and
phenotypes 		All alleles(32) : Targeted, other(1) Gene trapped(31)
Polymorphisms SNPs within 2kb(132 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cell morphogenesis, protein amino acid phosphorylation...
Component cytoplasm
Function ATP binding, kinase activity...
External Resources: FuncBase
Expression Literature Summary: (1 records)
Data Summary: Assays (1)    Results (4)    Tissues (3)
Theiler Stages: 28
  Assay Type Assays   Results
      RNA in situ 1   4
cDNA source data(28)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(29) cDNA(29)
Microarray probesets(4)
Other database
links
EC 2.7.11.1
Ensembl Gene Model ENSMUSG00000024576
DoTS DT.101171666, DT.101283768, DT.101388473, DT.101388474, DT.110756546, DT.495165, DT.94377142, DT.94421618, DT.99865035
Consensus CDS Project CCDS37838.1
DFCI TC1572012, TC1584994, TC1605869, TC1632500, TC1643294, TC1711046
Entrez Gene 93687
International Mouse Knockout Project Status Csnk1a1
Protein
domains
InterPro ID Description
IPR000719 Protein kinase, catalytic domain
IPR008271 Serine/threonine-protein kinase, active site
IPR011009 Protein kinase-like domain
IPR017441 Protein kinase, ATP binding site
IPR017442 Serine/threonine-protein kinase-like domain
Graphical View of Protein Domain Structure
References
(Earliest) J:46689 McInnes C et al., "Tissue-specific distribution of mouse casein kinase I alpha mRNA." DNA Seq 1997;8(1-2):55-7
(Latest) J:146202 Bidere N et al., "Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival." Nature 2009 Mar 5;458(7234):92-6
All references(13)
Other
accession IDs 		MGI:1914042, MGI:1915311, MGI:1926085
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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