Symbol
Name
ID
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Synonyms
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Dchil, Osteoactivin
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(79)
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Alleles
and
phenotypes
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All alleles(4) :
Targeted, knock-out(1)
Gene trapped(2)
Spontaneous(1)
| Homozygous mutants exhibit dispersed pigmentation of the iris, deterioration of the posterior iris epithelium and slit-like transillumination defects. The mutation contributes to glaucoma, especially in combination with the brown coat color mutation. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (1)
Phenotype Images (3)
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Polymorphisms
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SNPs within 2kb(111 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (2 records)
Data Summary:
Assays (3)
Results (21)
Tissues (12)
Images (12)
Theiler Stages: 15,17,22,26,28
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Assay Type |
Assays |
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Results |
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RNA in situ |
3 |
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21 |
cDNA source data(43)
External Resources:
Allen Brain Atlas
GENSAT
GEO
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Molecular
reagents
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All nucleic(50)
Genomic(4)
cDNA(46)
Microarray probesets(2)
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Other database
links
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Protein
domains
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Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:54013
Chang B et al.,
"Interacting loci cause severe iris atrophy and glaucoma in DBA/2J mice."
Nat Genet 1999 Apr;21(4):405-9
(Latest)
J:153818
Chung JS et al.,
"Binding of DC-HIL to dermatophytic fungi induces tyrosine phosphorylation and potentiates antigen presenting cell function."
J Immunol 2009 Oct 15;183(8):5190-8
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All references(25)
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Other
accession IDs
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MGI:1336203, MGI:1933809
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