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Nrgn Gene Detail
 Symbol
Name
ID
Nrgn
neurogranin
MGI:1927184


Nomenclature History
Synonyms 0710001B06Rik, NG, NG/RC3, protein kinase C substrate, Pss1, RC3
Genetic Map
Chromosome 9
17.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 5)

Sequence Map
Chr9:37352550-37360294 bp, - strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; cattle; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Nrgn ± 2 cM)
TreeFam: TF342962
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000053310 Ensembl Gene Model | MGI Sequence Detail 7745 C57BL/6J ± Kb
transcript NM_022029 RefSeq | MGI Sequence Detail 1293 C57BL/6
polypeptide P60761 UniProt | EBI | MGI Sequence Detail 78 Not Applicable
For the selected sequences
All sequences(19)
Alleles
and
phenotypes
All alleles(3) : Targeted, other(2) Gene trapped(1)
Homozygotes for a targeted null mutation exhibit impaired spatial learning and altered hippocampal short- and long-term plasticity. Heterozygotes show milder effects.
Polymorphisms RFLP(1) SNPs within 2kb(46 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(6)
Process protein kinase cascade
Component cell junction, cell projection...
Function calmodulin binding
External Resources: MouseFunc
Expression Literature Summary: (5 records)
Data Summary: Assays (2)    Results (12)    Tissues (1)    Images (2)
Theiler Stages: 28
  Assay Type Assays   Results
      Northern blot 2   12
cDNA source data(4)
External Resources: Allen Brain Atlas  GENSAT  GEO 
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000053310
DoTS DT.492376, DT.97354017
DFCI TC1575729
NIA Mouse Gene Index U030689
Entrez Gene 64011
International Mouse Knockout Project Status Nrgn
Protein
domains
InterPro ID Description
IPR000048 IQ calmodulin-binding region
Graphical View of Protein Domain Structure
References
(Earliest) J:16935 Danielson PE et al., "Chromosomal mapping of mouse genes expressed selectively within the central nervous system." Genomics 1994 Feb;19(3):454-61
(Latest) J:139387 Marzban H et al., "A novel transverse expression domain in the mouse cerebellum revealed by a neurofilament-associated antigen." Neuroscience 2008 Jun 2;153(4):1190-201
All references(19)
Other
accession IDs
MGD-MRK-16623, MGI:1915658, MGI:2143128, MGI:2143450, MGI:99834

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory