About   Help   FAQ
Acsl3 Gene Detail
 Symbol
Name
ID
Acsl3
acyl-CoA synthetase long-chain family member 3
MGI:1921455


Nomenclature History
Synonyms 2610510B12Rik, C85929, Facl3
Genetic Map
Chromosome 1
24.1 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 4)

Sequence Map
Chr1:78654400-78703562 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Acsl3 ± 2 cM)
Protein SuperFamily: human long-chain-fatty-acid-CoA ligase
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000033118 VEGA Gene Model | MGI Sequence Detail 49163 C57BL/6J ± Kb
transcript NM_028817 RefSeq | MGI Sequence Detail 3950 C57BL/6
polypeptide Q9CZW4 UniProt | EBI | MGI Sequence Detail 720 Not Applicable
For the selected sequences
All sequences(29)
Alleles
and
phenotypes
All alleles(7) : Gene trapped(7)
Polymorphisms SNPs within 2kb(200 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process fatty acid metabolic process, lipid metabolic process...
Component endoplasmic reticulum, integral to membrane...
Function ATP binding, catalytic activity...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression Literature Summary: (1 records)
Data Summary: Assays (2)    Results (12)    Tissues (2)
Theiler Stages: 24,28
  Assay Type Assays   Results
      RT-PCR 2   12
cDNA source data(9)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents
All nucleic(10) cDNA(9) Primer pair(1)
Microarray probesets(1)
Pathways
fatty acid β-oxidation I
fatty acid β-oxidation II (core pathway)
fatty acid activation
γ-linolenate biosynthesis II (animals)
Other database
links
EC 6.2.1.3
Ensembl Gene Model ENSMUSG00000032883
Consensus CDS Project CCDS15087.1
DFCI TC1575095, TC1606937, TC1759157
Entrez Gene 74205
VEGA Gene Model OTTMUSG00000033118
International Mouse Knockout Project Status Acsl3
Protein
domains
InterPro ID Description
IPR000873 AMP-dependent synthetase/ligase
IPR020845 AMP-binding, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:60984 Ko MS et al., "Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development." Development 2000 Apr;127(8):1737-49
(Latest) J:120282 de Jong H et al., "Ontogeny of mRNA expression and activity of long-chain acyl-CoA synthetase (ACSL) isoforms in Mus musculus heart." Biochim Biophys Acta 2007 Jan;1771(1):75-82
All references(9)
Other
accession IDs
MGI:2138711

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/06/2010
MGI_4.32
Web browser compatibility
The Jackson Laboratory