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Rd3 Gene Detail
 Symbol
Name
ID
Rd3
retinal degeneration 3
MGI:1921273


Nomenclature History
Synonyms 3322402L07Rik, rd-3, rd3
Genetic Map
Chromosome 1
108.0 cM, cytoband H6
Detailed Genetic Map ± 1 cM
 
Mapping data( 10)

Sequence Map
Chr1:193801270-193809795 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Rd3 ± 2 cM)
TreeFam: TF331573
Sequences
Representative Sequences Length Strain/Species Flank
genomic 74023 NCBI Gene Model | MGI Sequence Detail 8526 C57BL/6J ± Kb
transcript NM_023727 RefSeq | MGI Sequence Detail 1336 C57BL/6
polypeptide Q8BRE0 UniProt | EBI | MGI Sequence Detail 195 Not Applicable
For the selected sequences
All sequences(26)
Alleles
and
phenotypes
All alleles(2) : Gene trapped(1) Spontaneous(1)
Homozygotes for a spontaneous mutation exhibit retinal degeneration, beginning at 3 weeks of age, characterized by complete loss of photoreceptor rod cells by 5 weeks, and cones by 8 weeks.
Polymorphisms SNPs within 2kb(75 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(2)
Process response to stimulus, visual perception...
External Resources: MouseFunc
Expression Literature Summary: (1 records)
Data Summary: Assays (1)    Results (6)    Tissues (3)    Images (7)
Theiler Stages: 28
  Assay Type Assays   Results
      RNA in situ 1   6
cDNA source data(18)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(19) cDNA(19)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000049353
DoTS DT.101282900, DT.87056734, DT.91553149, DT.94176082
UniGene 274393
DFCI TC1584970, TC1604759, TC1615224, TC1630611
NIA Mouse Gene Index U001299
Entrez Gene 74023
International Mouse Knockout Project Status Rd3
References
(Earliest) J:4364 Bell JR et al., "Genomic structure, chromosomal location, and evolution of the mouse Hox 8 gene [published erratum appears in Genomics 1993 Sep;17(3):800]" Genomics 1993 Apr;16(1):123-31
(Latest) J:136923 Danciger M et al., "Genetic modifiers of retinal degeneration in the rd3 mouse." Invest Ophthalmol Vis Sci 2008 Jul;49(7):2863-9
All references(15)
Other
accession IDs
MGD-MRK-13810, MGD-MRK-13813, MGI:97884

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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