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Aldh1b1 Gene Detail
 Symbol
Name
ID
Aldh1b1
aldehyde dehydrogenase 1 family, member B1
MGI:1919785

Nomenclature History
Synonyms 2700007F14Rik
Genetic Map
Chromosome 4
cytoband B2
 
Mapping data( 2)
Sequence Map
Chr4:45811894-45817476 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: NAD-dependent aldehyde dehydrogenase
TreeFam: TF300455
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000006730 VEGA Gene Model | MGI Sequence Detail 5583 C57BL/6J ± Kb
transcript NM_028270 RefSeq | MGI Sequence Detail 2302 C57BL/6
polypeptide Q9CZS1 UniProt | EBI | MGI Sequence Detail 519 Not Applicable
For the selected sequences
All sequences(22)
Alleles
and
phenotypes 		All alleles(1) : Targeted, knock-out(1)
Polymorphisms SNPs within 2kb(40 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process metabolic process, oxidation reduction...
Component mitochondrion
Function aldehyde dehydrogenase (NAD) activity, oxidoreductase activity...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression Literature Summary: (2 records)
Data Summary: Assays (1)    Results (1)    Tissues (1)    Images (1)
Theiler Stages: 22
  Assay Type Assays   Results
      RNA in situ 1   1
cDNA source data(74)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(75) cDNA(74) Primer pair(1)
Microarray probesets(2)
Pathways
fatty acid α-oxidation
L-lactaldehyde degradation (aerobic)
oxidative ethanol degradation I
Other database
links
EC 1.2.1.3
Ensembl Gene Model ENSMUSG00000035561
DoTS DT.532400
Consensus CDS Project CCDS18139.1
UniGene 331583
DFCI TC1574401
NIA Mouse Gene Index U004275
Entrez Gene 72535
VEGA Gene Model OTTMUSG00000006730
International Mouse Knockout Project Status Aldh1b1
Protein
domains
InterPro ID Description
IPR015590 Aldehyde dehydrogenase
IPR016160 Aldehyde dehydrogenase, conserved site
IPR016161 Aldehyde/histidinol dehydrogenase
IPR016162 Aldehyde dehydrogenase, N-terminal
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J et al., "Functional annotation of a full-length mouse cDNA collection." Nature 2001 Feb 8;409(6821):685-90
(Latest) J:145577 Levi BP et al., "Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems." Blood 2009 Feb 19;113(8):1670-80
All references(8)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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