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Card11 Gene Detail
 Symbol
Name
ID
Card11
caspase recruitment domain family, member 11
MGI:1916978

Nomenclature History
Synonyms 0610008L17Rik, 2410011D02Rik, BIMP3, CARMA1
Genetic Map
Chromosome 5
Syntenic
 
Mapping data( 1)
Sequence Map
Chr5:141348953-141476446 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; cattle; dog, domestic    (Mammalian Orthology)
TreeFam: TF351139
Sequences
Representative Sequences Length Strain/Species Flank
genomic 108723 NCBI Gene Model | MGI Sequence Detail 127494 C57BL/6J ± Kb
transcript NM_175362 RefSeq | MGI Sequence Detail 4112 -
polypeptide Q8CIS0 UniProt | EBI | MGI Sequence Detail 1159 Not Applicable
For the selected sequences
All sequences(19)
Alleles
and
phenotypes 		All alleles(6) : Targeted, knock-out(3) Targeted, other(1) Chemically induced(2)
Mice homozygous for a targeted null mutation exhibit defects in antigen receptor signalling in both T and B lymphocytes.
Polymorphisms PCR(1) SNPs within 2kb(421 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process positive regulation of B cell proliferation, positive regulation of I-kappaB kinase/NF-kappaB cascade...
Component cytoplasm, intracellular...
Function protein binding
External Resources: FuncBase
Expression cDNA source data(11)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(12) cDNA(11) Primer pair(1)
Microarray probesets(1)
Other database
links
Ensembl Gene Model ENSMUSG00000036526
DoTS DT.40137848, DT.60104704, DT.94127319
UniGene 46187
DFCI TC1585872, TC1681645
NIA Mouse Gene Index U026896
Entrez Gene 108723
International Mouse Knockout Project Status Card11
Protein
domains
InterPro ID Description
IPR001315 Caspase Recruitment
IPR001478 PDZ/DHR/GLGF
IPR011029 DEATH-like
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J et al., "Functional annotation of a full-length mouse cDNA collection." Nature 2001 Feb 8;409(6821):685-90
(Latest) J:156178 Long M et al., "Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor." Immunity 2009 Dec 18;31(6):921-31
All references(30)
Other
accession IDs 		MGI:1915575
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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