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Sncb Gene Detail
 Symbol
Name
ID
Sncb
synuclein, beta
MGI:1889011


Nomenclature History
Synonyms betaSYN
Genetic Map
Chromosome 13
35.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 3)

Sequence Map
Chr13:54860221-54867956 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Sncb ± 2 cM)
Protein SuperFamily: synuclein
TreeFam: TF332776
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000032668 VEGA Gene Model | MGI Sequence Detail 7736 C57BL/6J ± Kb
transcript NM_033610 RefSeq | MGI Sequence Detail 1210 -
polypeptide Q91ZZ3 UniProt | EBI | MGI Sequence Detail 133 Not Applicable
For the selected sequences
All sequences(15)
Alleles
and
phenotypes
All alleles(2) : Targeted, knock-out(1) Targeted, other(1)
Mice homozygous for disruptions in this gene display an essentially normal phenotype.
Polymorphisms PCR(1) SNPs within 2kb(51 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(6)
Process dopamine metabolic process, negative regulation of neuron apoptosis...
Component cytoplasm, mitochondrion...
External Resources: MouseFunc
Expression Literature Summary: (5 records)
Data Summary: Assays (1)    Results (15)    Tissues (9)    Images (15)
Theiler Stages: 22,24,26,28
  Assay Type Assays   Results
      RNA in situ 1   15
cDNA source data(23)
External Resources: GENSAT  GEO 
Molecular
reagents
All nucleic(25) cDNA(24) Primer pair(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000034891
DoTS DT.486814
UniGene 200843
DFCI TC1581008
NIA Mouse Gene Index U034804
Entrez Gene 104069
VEGA Gene Model OTTMUSG00000032668
International Mouse Knockout Project Status Sncb
Protein
domains
InterPro ID Description
IPR001058 Synuclein
IPR002461 Beta-synuclein
Graphical View of Protein Domain Structure
References
(Earliest) J:50153 Lavedan C, "The synuclein family." Genome Res 1998 Sep;8(9):871-80
(Latest) J:150768 Okado H et al., "The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex." Dev Biol 2009 Jul 15;331(2):140-51
All references(13)
Other
accession IDs
MGI:2138328

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory