Symbol
Name
ID
|
Apba1
amyloid beta (A4) precursor protein binding, family A, member 1
MGI:1860297
|
Nomenclature History
|
|
|
Synonyms
|
6430513E09Rik, Lin-10, Mint, Mint1, X11, X11alpha
|
|
Genetic Map
|
|
Chromosome 19
|
Syntenic
|
|
|
|
Mapping data(
1)
|
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(29)
|
Alleles
and
phenotypes
|
All alleles(3) :
Targeted, knock-out(2)
Targeted, other(1)
| Animals carrying a homozygous mutation of this gene have reduced body size. |
|
|
Polymorphisms
|
SNPs within 2kb(1366 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (3 records)
Data Summary:
Assays (1)
Results (17)
Tissues (8)
Theiler Stages: 18,20,21,22,23,24,25,28
| |
Assay Type |
Assays |
|
Results |
| |
Western blot |
1 |
|
17 |
cDNA source data(61)
External Resources:
Allen Brain Atlas
GEO
|
Molecular
reagents
|
All nucleic(61)
cDNA(61)
Antibodies(2)
Microarray probesets(1)
|
Other database
links
|
|
Protein
domains
|
|
|
References
|
(Earliest)
J:62652
Borg JP et al.,
"Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting."
J Biol Chem 1998 Nov 27;273(48):31633-6
(Latest)
J:144412
Saito Y et al.,
"X11 proteins regulate the translocation of amyloid beta-protein precursor (APP) into detergent-resistant membrane and suppress the amyloidogenic cleavage of APP by beta-site-cleaving enzyme in brain."
J Biol Chem 2008 Dec 19;283(51):35763-71
|
All references(13)
|
Other
accession IDs
|
MGI:2442991
|
