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| Nomenclature |
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Symbol:
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Hprt1b-m2
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Name:
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hypoxanthine guanine phosphoribosyl transferase 1;
hypoxanthine guanine phosphoribosyl transferase B, mutation 2
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MGI ID: |
MGI:1857298 |
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Synonyms: |
Hprt-bm2, hprtmb2 |
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Gene:
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Hprt1
Location:
ChrX:50341314-50374836 bp, + strand
Genetic Position: ChrX,
17.0 cM, cytoband A6
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Transgene
origin |
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Germline Transmission:
| Earliest citation of germline transmission:
J:15485
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Parent Cell Line:
| CCE/EK.CCE (ES Cell) |
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Strain of Origin:
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129S/SvEv-Gpi1c
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Transgene
description |
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Transgene
Type: |
Transgenic (random, gene disruption) |
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Mutation: |
Insertion |
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A retroviral sequence was inserted into intron 5. (J:3354) |
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Phenotype
summary
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Phenotype Summary by Mammalian Phenotype terms
(show or
hide all annotated terms)
Genotypes are listed in the next section.
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Key:
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| hm |
homozygous |
ht |
heterozygous |
| cn |
conditional genotype |
cx |
complex: > 1 genome feature |
| tg |
involves transgenes |
ot |
other: hemizygous, indeterminate,... |
| N |
normal phenotype |
 |
expected model not found |
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Phenotypic
data by
genotype
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Phenotypic Data by Genotype
(show or
hide all phenotypic details)
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| References |
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Original: |
J:15485
Kuehn MR et al.,
"A potential animal model for Lesch-Nyhan syndrome through introduction of HPRT mutations into mice."
Nature 1987 Mar 19-25;326(6110):295-8
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All: |
4 reference(s)
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