Symbol
Name
ID
|
|
|
Synonyms
|
FREAC8
|
|
Genetic Map
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(10)
|
Alleles
and
phenotypes
|
All alleles(3) :
Targeted, knock-out(2)
Spontaneous(1)
| Homozygotes for a spontaneous mutation exhibit microphthalmia, fusion of the lens and cornea, and other lens abnormalities. Homozygotes for a null mutation display microphthalmia, fusion of the lens and cornea, other corneal and lens abnormalities, and may fail to open their eyes. |
Associated Human Diseases (2)
Alleles Annotated to Human Diseases (1)
|
|
Polymorphisms
|
SNPs within 2kb(15 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (20 records)
Data Summary:
Assays (1)
Results (1)
Tissues (1)
Images (1)
Theiler Stages: 17
| |
Assay Type |
Assays |
|
Results |
| |
RNA in situ |
1 |
|
1 |
External Resources:
GEO
|
Molecular
reagents
|
All nucleic(2)
Genomic(2)
Microarray probesets(2)
|
Other database
links
|
|
Protein
domains
|
| InterPro ID |
Description |
| IPR001766 |
Transcription factor, fork head |
| IPR011991 |
Winged helix repressor DNA-binding |
| IPR018122 |
Transcription factor, fork head, conserved site |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:6131
Sanyal S et al.,
"Dysgenetic lens (dyl)--a new gene in the mouse."
Invest Ophthalmol Vis Sci 1979 Jun;18(6):642-5
(Latest)
J:151537
Maeda A et al.,
"Transcription factor GATA-3 is essential for lens development."
Dev Dyn 2009 Jul 21;238(9):2280-2291
|
All references(28)
|
Other
accession IDs
|
MGD-MRK-9263, MGI:95261
|
