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Ror1 Gene Detail
 Symbol
Name
ID
Ror1
receptor tyrosine kinase-like orphan receptor 1
MGI:1347520

Nomenclature History
Synonyms 2810404D04Rik, Ntrkr1
Genetic Map
Chromosome 4
49.6 cM, cytoband C6
Detailed Genetic Map ± 1 cM
 
Mapping data( 4)

Sequence Map
Chr4:99768396-100117370 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Ror1 ± 2 cM)
Protein SuperFamily: tyrosine-protein kinase transmembrane receptor ROR
TreeFam: TF106465
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000008027 VEGA Gene Model | MGI Sequence Detail 348975 C57BL/6J ± Kb
transcript NM_013845 RefSeq | MGI Sequence Detail 3542 C57BL/6
polypeptide Q9Z139 UniProt | EBI | MGI Sequence Detail 937 Not Applicable
For the selected sequences
All sequences(32)
Alleles
and
phenotypes 		All alleles(4) : Targeted, knock-out(1) Gene trapped(3)
Mice homozygous for disruptions in this gene die within the first day after birth from respiratory defects.
Polymorphisms RFLP(1) SNPs within 2kb(1988 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process protein amino acid phosphorylation, transmembrane receptor protein tyrosine kinase signaling pathway...
Component integral to membrane, integral to plasma membrane...
Function ATP binding, kinase activity...
External Resources: FuncBase
Expression Literature Summary: (4 records)
Data Summary: Assays (2)    Results (127)    Tissues (125)    Images (29)
Theiler Stages: 11,13,15,17,20,21,22
  Assay Type Assays   Results
      RNA in situ 2   127
cDNA source data(9)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(13) Genomic(2) cDNA(9) Primer pair(1) Other(1)
Microarray probesets(2)
Other database
links
EC 2.7.10.1
Ensembl Gene Model ENSMUSG00000035305
DoTS DT.110802590, DT.110802647, DT.55256966, DT.91306656
Consensus CDS Project CCDS18389.1
DFCI TC1582654, TC1672998, TC1756683
NIA Mouse Gene Index U004540
Entrez Gene 26563
VEGA Gene Model OTTMUSG00000008027
International Mouse Knockout Project Status Ror1
Protein
domains
InterPro ID Description
IPR000001 Kringle
IPR000719 Protein kinase, catalytic domain
IPR001245 Tyrosine-protein kinase, catalytic domain
IPR003598 Immunoglobulin subtype 2
IPR007110 Immunoglobulin-like
IPR008266 Tyrosine-protein kinase, active site
IPR011009 Protein kinase-like domain
IPR013098 Immunoglobulin I-set
IPR013783 Immunoglobulin-like fold
IPR013806 Kringle-like fold
IPR016247 Tyrosine-protein kinase, receptor ROR, subgroup
IPR018056 Kringle, conserved site
IPR018059 Kringle, subgroup
IPR020067 Frizzled-like domain
IPR020635 Tyrosine-protein kinase, subgroup, catalytic domain
IPR020685 Tyrosine-protein kinase
Graphical View of Protein Domain Structure
References
(Earliest) J:57217 Oishi I et al., "Spatio-temporally regulated expression of receptor tyrosine kinases, mRor1, mRor2, during mouse development: implications in development and function of the nervous system." Genes Cells 1999 Jan;4(1):41-56
(Latest) J:122989 Visel A et al., "GenePaint.org: an atlas of gene expression patterns in the mouse embryo." Nucleic Acids Res 2004 Jan 1;32(Database issue):D552-6
All references(8)
Other
accession IDs 		MGI:1919426
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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