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Slc30a4 Gene Detail
 Symbol
Name
ID
Slc30a4
solute carrier family 30 (zinc transporter), member 4
MGI:1345282


Nomenclature History
Synonyms Znt4
Genetic Map
Chromosome 2
69.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 3)

Sequence Map
Chr2:122506969-122528399 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Slc30a4 ± 2 cM)
Protein SuperFamily: cation efflux protein
TreeFam: TF313382
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000015670 VEGA Gene Model | MGI Sequence Detail 21431 C57BL/6J ± Kb
transcript NM_011774 RefSeq | MGI Sequence Detail 5476 -
polypeptide O35149 UniProt | EBI | MGI Sequence Detail 430 Not Applicable
For the selected sequences
All sequences(25)
Alleles
and
phenotypes
All alleles(3) : Targeted, other(2) Spontaneous(1)
Homozygous mutant dams produce zinc-deficient milk that is lethal to all nursing pups. Pleiotropic defects observed in mutant males and females include otolith degeneration, impaired motor coordination, alopecia, and dermatitis.
Associated Human Diseases (1)   Alleles Annotated to Human Diseases (1)  
Polymorphisms RFLP(1) SNPs within 2kb(78 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(12)
Process cation transport, ion transport...
Component endosome, integral to membrane...
Function cation transmembrane transporter activity, zinc ion binding...
External Resources: MouseFunc
Expression Literature Summary: (1 records)
Data Summary: Assays (1)    Results (6)    Tissues (1)    Images (1)
Theiler Stages: 28
  Assay Type Assays   Results
      RT-PCR 1   6
cDNA source data(68)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(73) Genomic(4) cDNA(68) Primer pair(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000005802
DoTS DT.101363085, DT.530102
UniGene 27801
DFCI TC1631525, TC1638683
NIA Mouse Gene Index U023280
Entrez Gene 22785
VEGA Gene Model OTTMUSG00000015670
International Mouse Knockout Project Status Slc30a4
Protein
domains
InterPro ID Description
IPR002524 Cation efflux protein
Graphical View of Protein Domain Structure
References
(Earliest) J:30724 Dickie MM, "lm" Mouse News Lett 1969;41():30-1
(Latest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), "The Transcriptional Landscape of the Mammalian Genome" Science 2005;309(5740):1559-1563
All references(19)
Other
accession IDs
MGD-MRK-11815, MGI:1196348, MGI:96792

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory