Symbol
Name
ID
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Genetic Map
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Chromosome 7
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Syntenic
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Mapping data(
2)
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(17)
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Alleles
and
phenotypes
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All alleles(15) :
Targeted, knock-out(4)
Targeted, other(10)
Gene trapped(1)
| Homozygotes for targeted null mutations exhibit blockage of intra-thymic lymphocyte development at the double negative stage and absence of mature peripheral T cells. |
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Polymorphisms
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SNPs within 2kb(60 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
|
Literature Summary: (1 records)
Data Summary:
Assays (2)
Results (7)
Tissues (4)
Theiler Stages: 22,24,26,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
2 |
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7 |
cDNA source data(18)
External Resources:
Allen Brain Atlas
GENSAT
GEO
ArrayExpress
|
Molecular
reagents
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All nucleic(20)
cDNA(19)
Primer pair(1)
Microarray probesets(2)
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Other database
links
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Protein
domains
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| InterPro ID |
Description |
| IPR008359 |
Linker-for-activation of T cells (LAT) protein |
Graphical View
of Protein Domain Structure
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References
|
(Earliest)
J:49412
Zhang W et al.,
"LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation."
Immunity 1998 Aug;9(2):239-46
(Latest)
J:155482
Syed SN et al.,
"Both FcgammaRIV and FcgammaRIII are essential receptors mediating type II and type III autoimmune responses via FcRgamma-LAT-dependent generation of C5a."
Eur J Immunol 2009 Dec;39(12):3343-56
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All references(67)
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Analysis Tools
MGI BioMart