Symbol
Name
ID
|
|
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Synonyms
|
Csfgm, Gm-CSf, MGI-IGM
|
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Genetic Map
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Sequence Map
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Mammalian
homology
|
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Sequences
|
All sequences(23)
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Alleles
and
phenotypes
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All alleles(3) :
Targeted, knock-out(2)
Targeted, other(1)
| Homozygotes for targeted null mutations exhibit lung abnormalities with lymphocytic infiltration and accumulation of surfactant lipids. Litter sizes from homozygous breeding pairs are smaller at weaning due to perinatal mortality. |
Associated Human Diseases (3)
Alleles Annotated to Human Diseases (3)
|
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Polymorphisms
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All PCR and RFLP(16) :
PCR(9)
RFLP(7)
SNPs within 2kb(62 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
|
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Expression
|
Literature Summary: (7 records)
Data Summary:
Assays (4)
Results (42)
Tissues (26)
Theiler Stages: 1,2,3,5,21,22,23,24,25,26,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
3 |
|
36 |
| |
Nuclease S1 |
1 |
|
6 |
cDNA source data(12)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
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All nucleic(36)
Genomic(14)
cDNA(12)
Primer pair(7)
Other(3)
Microarray probesets(2)
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Other database
links
|
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Protein
domains
|
| InterPro ID |
Description |
| IPR000773 |
Granulocyte-macrophage colony-stimulating factor |
| IPR009079 |
Four-helical cytokine-like, core |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:7492
Gough NM et al.,
"Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte-macrophage colony stimulating factor."
Nature 1984 Jun 28-Jul 4;309(5971):763-7
(Latest)
J:155684
Dolcetti L et al.,
"Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF."
Eur J Immunol 2010 Jan;40(1):22-35
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All references(228)
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Other
accession IDs
|
MGD-MRK-2187, MGI:88531
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Analysis Tools
MGI BioMart
