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Hsd17b10 Gene Detail
 Symbol
Name
ID
Hsd17b10
hydroxysteroid (17-beta) dehydrogenase 10
MGI:1333871

Nomenclature History
Synonyms Ads9, ERAB, Hadh2
Genetic Map
Chromosome X
Syntenic
 
Mapping data( 2)
Sequence Map
ChrX:148436388-148438985 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: short-chain dehydrogenase
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000019648 VEGA Gene Model | MGI Sequence Detail 2598 C57BL/6J ± Kb
transcript NM_016763 RefSeq | MGI Sequence Detail 938 C57BL/6
polypeptide O08756 UniProt | EBI | MGI Sequence Detail 261 Not Applicable
For the selected sequences
All sequences(21)
Polymorphisms SNPs within 2kb(4 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process metabolic process, oxidation reduction...
Component endoplasmic reticulum, mitochondrial inner membrane...
Function 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity, 3-hydroxyacyl-CoA dehydrogenase activity...
External Resources: FuncBase
Expression Literature Summary: (1 records)
cDNA source data(8)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(9) Genomic(1) cDNA(8)
Microarray probesets(2)
Pathways
fatty acid β-oxidation I
2-methylbutyrate biosynthesis
fatty acid β-oxidation II (core pathway)
isoleucine degradation
Other database
links
EC 1.1.1.178, 1.1.1.35
Ensembl Gene Model ENSMUSG00000025260
DoTS DT.538023
Consensus CDS Project CCDS30471.1
DFCI TC1572702
NIA Mouse Gene Index U020320
Entrez Gene 15108
VEGA Gene Model OTTMUSG00000019648
International Mouse Knockout Project Status Hsd17b10
Protein
domains
InterPro ID Description
IPR002198 Short-chain dehydrogenase/reductase SDR
IPR002347 Glucose/ribitol dehydrogenase
IPR016040 NAD(P)-binding domain
IPR020904 Short-chain dehydrogenase/reductase, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:51470 Hansis C et al., "The gene for the Alzheimer-associated beta-amyloid-binding protein (ERAB) is differentially expressed in the testicular Leydig cells of the azoospermic by w/w(v) mouse." Eur J Biochem 1998 Nov 15;258(1):53-60
(Latest) J:151002 Pagliarini DJ et al., "A mitochondrial protein compendium elucidates complex I disease biology." Cell 2008 Jul 11;134(1):112-23
All references(14)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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