Symbol
Name
ID
|
|
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Synonyms
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mdkk-1
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Genetic Map
|
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Chromosome 19
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cytoband C2
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Mapping data(
1)
|
|
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Sequence Map
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Mammalian
homology
|
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Sequences
|
All sequences(14)
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Alleles
and
phenotypes
|
All alleles(2) :
Targeted, knock-out(1)
Targeted, other(1)
| Mice homozygous for a targeted mutation die at birth exhibiting absence of anterior head structures and forelimb malformations ranging from fusion of the distal-most limb elements to the appearance of ectopic preaxial and postaxial digits. |
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Polymorphisms
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SNPs within 2kb(40 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
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Expression
|
Literature Summary: (82 records)
Data Summary:
Assays (22)
Results (311)
Tissues (258)
Images (69)
Theiler Stages: 1,2,3,4,5,8,9,10,11,12,13,14,15,16,17,19,20,21,22,23,24,26,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
5 |
|
41 |
| |
In situ reporter (knock in) |
1 |
|
6 |
| |
RNA in situ |
15 |
|
262 |
| |
Immunohistochemistry |
1 |
|
2 |
cDNA source data(12)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(25)
cDNA(13)
Primer pair(9)
Other(3)
Antibodies(1)
Microarray probesets(2)
|
Other database
links
|
|
Protein
domains
|
| InterPro ID |
Description |
| IPR006796 |
Dickkopf, N-terminal cysteine-rich |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:51745
Glinka A et al.,
"Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction."
Nature 1998 Jan 22;391(6665):357-62
(Latest)
J:155223
Suomalainen M et al.,
"Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells."
Dev Dyn 2009 Oct 5;239(1):364-372
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All references(101)
|
Analysis Tools
MGI BioMart