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Cyba Gene Detail
 Symbol
Name
ID
Cyba
cytochrome b-245, alpha polypeptide
MGI:1316658


Nomenclature History
Synonyms b558, cytochrome beta-558, p22 phox
Genetic Map
Chromosome 8
67.0 cM, cytoband E1
Detailed Genetic Map ± 1 cM
 
Mapping data( 3)

Sequence Map
Chr8:124948679-124956808 bp, - strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Cyba ± 2 cM)
Protein SuperFamily: cytochrome b558, alpha subunit
TreeFam: TF328901
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000006519 Ensembl Gene Model | MGI Sequence Detail 8130 C57BL/6J ± Kb
transcript NM_007806 RefSeq | MGI Sequence Detail 764 C57BL/6
polypeptide Q61462 UniProt | EBI | MGI Sequence Detail 192 Not Applicable
For the selected sequences
All sequences(30)
Alleles
and
phenotypes
All alleles(6) : Gene trapped(5) Chemically induced(1)
Mice homozygous for an ENU-induced mutation exhibit defects in balance, absence of otoconia, and an inability of phagocytes to produce bacteria-destroying reactive oxygen species.
Polymorphisms SNPs within 2kb(75 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(10)
Process electron transport chain, oxidation reduction...
Component cytoplasm, membrane...
Function heme binding, iron ion binding...
External Resources: MouseFunc
Expression Literature Summary: (3 records)
Data Summary: Assays (2)    Results (10)    Tissues (8)    Images (4)
Theiler Stages: 22,25,28
  Assay Type Assays   Results
      RT-PCR 1   1
      Immunohistochemistry 1   9
cDNA source data(82)
External Resources: Allen Brain Atlas  GENSAT  GEO 
Molecular
reagents
All nucleic(83) cDNA(82) Primer pair(1) Antibodies(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000006519
DoTS DT.101362035, DT.534805, DT.99863317
UniGene 271671
DFCI TC1574417, TC1590971, TC1592822, TC1601856
NIA Mouse Gene Index U030350
Entrez Gene 13057
International Mouse Knockout Project Status Cyba
Protein
domains
InterPro ID Description
IPR007732 Cytochrome b558 alpha-subunit
Graphical View of Protein Domain Structure
References
(Earliest) J:51302 Sumimoto H et al., "Complementary DNA for the mouse homolog of the small subunit of human cytochrome b558." Biochem Biophys Res Commun 1989 Dec 15;165(2):902-6
(Latest) J:148113 Sugimura Y et al., "Prevention of neural tube defects by loss of function of inducible nitric oxide synthase in fetuses of a mouse model of streptozotocin-induced diabetes." Diabetologia 2009 May;52(5):962-71
All references(15)
Other
accession IDs
MGI:3526724

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory