Symbol
Name
ID
|
|
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Synonyms
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Coch-5B2, D12H14S564E
|
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Genetic Map
|
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Sequence Map
|
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Mammalian
homology
|
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Sequences
|
All sequences(21)
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Alleles
and
phenotypes
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All alleles(3) :
Targeted, knock-out(1)
Targeted, other(2)
| Homozygotes for a point mutation have vestibular and hearing dysfunctions that worsen with age. Homozyogtes for a null allele have no abnormal phenotype. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (1)
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Polymorphisms
|
RFLP(1)
SNPs within 2kb(60 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
|
|
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Expression
|
Literature Summary: (3 records)
Data Summary:
Assays (3)
Results (32)
Tissues (14)
Theiler Stages: 23,28
| |
Assay Type |
Assays |
|
Results |
| |
Western blot |
1 |
|
2 |
| |
RT-PCR |
1 |
|
2 |
| |
In situ reporter (knock in) |
1 |
|
28 |
cDNA source data(14)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
|
All nucleic(16)
cDNA(15)
Primer pair(1)
Antibodies(1)
Microarray probesets(2)
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Other database
links
|
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Protein
domains
|
Graphical View
of Protein Domain Structure
|
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References
|
(Earliest)
J:39118
Crozet F et al.,
"Cloning of the genes encoding two murine and human cochlear unconventional type I myosins."
Genomics 1997 Mar 1;40(2):332-41
(Latest)
J:140594
Robertson NG et al.,
"A targeted Coch missense mutation: a knock-in mouse model for DFNA9 late-onset hearing loss and vestibular dysfunction."
Hum Mol Genet 2008 Nov 1;17(21):3426-34
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All references(14)
|
Other
accession IDs
|
MGI:2145007
|
