Symbol
Name
ID
|
Ehhadh
enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase
MGI:1277964
|
Nomenclature History
|
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Synonyms
|
1300002P22Rik, HD, L-bifunctional enzyme, L-PBE, MFP, MFP1
|
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Genetic Map
|
|
Chromosome 16
|
cytoband B1
|
|
|
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Mapping data(
2)
|
|
|
|
Sequence Map
|
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Mammalian
homology
|
|
|
Sequences
|
All sequences(15)
|
Alleles
and
phenotypes
|
All alleles(4) :
Targeted, knock-out(1)
Targeted, other(2)
Gene trapped(1)
| Mice homozygous for disruption of this gene display a normal phenotype. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (1)
Phenotype Images (3)
|
|
Polymorphisms
|
SNPs within 2kb(123 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (2 records)
Data Summary:
Assays (1)
Results (15)
Tissues (9)
Theiler Stages: 15,19,22,26,28
| |
Assay Type |
Assays |
|
Results |
| |
Northern blot |
1 |
|
15 |
cDNA source data(82)
External Resources:
Allen Brain Atlas
GENSAT
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(83)
cDNA(82)
Primer pair(1)
Microarray probesets(2)
|
|
Pathways
|
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Other database
links
|
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Protein
domains
|
| InterPro ID |
Description |
| IPR001753 |
Crotonase, core |
| IPR006108 |
3-hydroxyacyl-CoA dehydrogenase, C-terminal |
| IPR006176 |
3-hydroxyacyl-CoA dehydrogenase, NAD binding |
| IPR006180 |
3-hydroxyacyl-CoA dehydrogenase, conserved site |
| IPR008927 |
6-phosphogluconate dehydrogenase, C-terminal-like |
| IPR013328 |
Dehydrogenase, multihelical |
| IPR016040 |
NAD(P)-binding domain |
| IPR018376 |
Enoyl-CoA hydratase/isomerase, conserved site |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:55395
Qi C et al.,
"Absence of spontaneous peroxisome proliferation in enoyl-CoA Hydratase/L-3-hydroxyacyl-CoA dehydrogenase-deficient mouse liver. Further support for the role of fatty acyl CoA oxidase in PPARalpha ligand metabolism."
J Biol Chem 1999 May 28;274(22):15775-80
(Latest)
J:151002
Pagliarini DJ et al.,
"A mitochondrial protein compendium elucidates complex I disease biology."
Cell 2008 Jul 11;134(1):112-23
|
All references(13)
|
Other
accession IDs
|
MGI:1921397
|
Analysis Tools
MGI BioMart