Symbol
Name
ID
|
|
|
Synonyms
|
alpha-synuclein, alphaSYN
|
|
Genetic Map
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(29)
|
Alleles
and
phenotypes
|
All alleles(4) :
Targeted, knock-out(3)
Targeted, other(1)
| Mice homozygous for disruptions in this gene display resistance to the effects of MPTP on dopamine levels. Otherwise, they show a normal phenotype. |
Associated Human Diseases (2)
Alleles Annotated to Human Diseases (1)
|
|
Polymorphisms
|
PCR(3)
SNPs within 2kb(555 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (11 records)
Data Summary:
Assays (2)
Results (26)
Tissues (16)
Theiler Stages: 22,23,25,28
| |
Assay Type |
Assays |
|
Results |
| |
RNA in situ |
1 |
|
18 |
| |
Northern blot |
1 |
|
8 |
cDNA source data(41)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
|
All nucleic(45)
cDNA(42)
Primer pair(3)
Microarray probesets(2)
|
Other database
links
|
|
Protein
domains
|
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:48620
Hsu LJ et al.,
"Expression pattern of synucleins (non-Abeta component of Alzheimer's disease amyloid precursor protein/alpha-synuclein) during murine brain development."
J Neurochem 1998 Jul;71(1):338-44
(Latest)
J:153557
Rappley I et al.,
"Lipidomic profiling in mouse brain reveals differences between ages and genders, with smaller changes associated with alpha-synuclein genotype."
J Neurochem 2009 Oct;111(1):15-25
|
All references(74)
|
