About   Help   FAQ
Tour our new Quick Search
Birc6 Gene Detail
 Symbol
Name
ID
Birc6
baculoviral IAP repeat-containing 6
MGI:1276108

Nomenclature History
Synonyms A430032G04Rik, A430040A19Rik, apollon, Bruce, D630005A10Rik
Genetic Map
Chromosome 17
cytoband E3
 
Mapping data( 3)
Sequence Map
Chr17:74927635-75102403 bp, + strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; cattle; dog, domestic; rat    (Mammalian Orthology)
TreeFam: TF105357
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000024073 Ensembl Gene Model | MGI Sequence Detail 174769 C57BL/6J ± Kb
transcript NM_007566 RefSeq | MGI Sequence Detail 16212 C57BL/6
polypeptide NP_031592 RefSeq | MGI Sequence Detail 4854 C57BL/6
For the selected sequences
All sequences(56)
Alleles
and
phenotypes 		All alleles(72) : Targeted, knock-out(2) Gene trapped(70)
Homozygous mice exhibit perinatal lethality and exhibit placental defects.
Polymorphisms SNPs within 2kb(534 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(9)
Process anti-apoptosis, labyrinthine layer development...
Component membrane fraction
Function protein binding, ubiquitin-protein ligase activity...
External Resources: MouseFunc
Expression Literature Summary: (5 records)
Data Summary: Assays (7)    Results (31)    Tissues (14)    Images (7)
Theiler Stages: 10,17,18,22,23,25,28
  Assay Type Assays   Results
      Western blot 2   6
      RNA in situ 1   1
      Northern blot 4   24
cDNA source data(24)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents 		All nucleic(28) cDNA(28) Antibodies(2)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000024073
DoTS DT.101127629, DT.101708241, DT.102544196, DT.103567868, DT.40139759, DT.40169940, DT.87057586, DT.91307295, DT.91336624, DT.91572247, DT.99839898
DFCI TC1577777, TC1619456, TC1623907, TC1632040, TC1634612, TC1668537, TC1717552
NIA Mouse Gene Index U018226, U376505
Entrez Gene 12211
International Mouse Knockout Project Status Birc6
Protein
domains
InterPro ID Description
IPR000608 Ubiquitin-conjugating enzyme, E2
IPR001370 Proteinase inhibitor I32, inhibitor of apoptosis
IPR016135 Ubiquitin-conjugating enzyme/RWD-like
References
(Earliest) J:48143 Hauser HP et al., "A giant ubiquitin-conjugating enzyme related to IAP apoptosis inhibitors." J Cell Biol 1998 Jun 15;141(6):1415-22
(Latest) J:137430 Pohl C et al., "Final stages of cytokinesis and midbody ring formation are controlled by BRUCE." Cell 2008 Mar 7;132(5):832-45
All references(20)
Other
accession IDs 		MGI:2442816, MGI:2444799, MGI:2444861, MGI:3034286
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
11/20/2009
MGI_4.31
Web browser compatibility 		The Jackson Laboratory