Symbol
Name
ID
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Synonyms
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6330412C24Rik, caPI3K, p110alpha
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(32)
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Alleles
and
phenotypes
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All alleles(17) :
Targeted, knock-out(2)
Targeted, other(5)
Gene trapped(10)
Phenotype Images (2)
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Polymorphisms
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PCR(1)
SNPs within 2kb(324 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (6 records)
Data Summary:
Assays (5)
Results (10)
Tissues (4)
Images (1)
Theiler Stages: 10,15,25,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
3 |
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6 |
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RNA in situ |
1 |
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1 |
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Northern blot |
1 |
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3 |
cDNA source data(19)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
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Molecular
reagents
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All nucleic(27)
Genomic(2)
cDNA(20)
Primer pair(4)
Other(1)
Microarray probesets(3)
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Other database
links
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Protein
domains
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| InterPro ID |
Description |
| IPR000008 |
C2 calcium-dependent membrane targeting |
| IPR000341 |
Phosphoinositide 3-kinase, ras-binding |
| IPR000403 |
Phosphatidylinositol 3-/4-kinase, catalytic |
| IPR001263 |
Phosphoinositide 3-kinase, accessory (PIK) domain |
| IPR002420 |
Phosphoinositide 3-kinase, C2 |
| IPR003113 |
Phosphatidylinositol 3-kinase, p85-binding |
| IPR008973 |
C2 calcium/lipid-binding domain, CaLB |
| IPR011009 |
Protein kinase-like domain |
| IPR015433 |
Phosphatidylinositol Kinase |
| IPR016024 |
Armadillo-type fold |
| IPR018936 |
Phosphatidylinositol 3/4-kinase, conserved site |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:47211
Klippel A et al.,
"The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity."
Mol Cell Biol 1994 Apr;14(4):2675-85
(Latest)
J:155716
Tamura N et al.,
"Specific role of phosphoinositide 3-kinase p110alpha in the regulation of phagocytosis and pinocytosis in macrophages."
Biochem J 2009 Oct 1;423(1):99-108
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All references(49)
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Other
accession IDs
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MGI:1917992
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Analysis Tools
MGI BioMart
