Symbol
Name
ID
|
|
|
Synonyms
|
mTcf-4B, mTcf-4E, Tcf-4, Tcf4, TCF4B, TCF4E
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Genetic Map
|
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Sequence Map
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Mammalian
homology
|
|
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Sequences
|
All sequences(69)
|
Alleles
and
phenotypes
|
All alleles(10) :
Targeted, knock-out(1)
Gene trapped(9)
| Animals homozygous for a targeted mutation exhibit intestinal epithelia abnormalities and die shortly after birth. |
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Polymorphisms
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SNPs within 2kb(786 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
|
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Expression
|
Literature Summary: (58 records)
Data Summary:
Assays (16)
Results (228)
Tissues (136)
Images (26)
Theiler Stages: 2,3,4,5,13,14,16,17,18,19,20,21,22,24,26,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
2 |
|
18 |
| |
RNA in situ |
14 |
|
210 |
cDNA source data(78)
External Resources:
Allen Brain Atlas
GEO
|
Molecular
reagents
|
All nucleic(87)
cDNA(80)
Primer pair(5)
Other(2)
Microarray probesets(3)
|
Other database
links
|
| Ensembl Gene Model |
ENSMUSG00000024985 |
| DoTS |
DT.101142313, DT.101357888, DT.101408432, DT.101408435, DT.110868652, DT.530294, DT.55185608, DT.87026948, DT.91412082, DT.94276508, DT.94276515 |
| UniGene |
139815 |
| DFCI |
TC1576789, TC1589368, TC1589691, TC1590945, TC1593611, TC1623547, TC1638533, TC1768387, TC1769434, TC1773383 |
| NIA Mouse Gene Index |
U019591 |
| Entrez Gene |
21416 |
| VEGA Gene Model |
OTTMUSG00000020410 |
| International Mouse Knockout Project Status |
Tcf7l2 |
|
Protein
domains
|
| InterPro ID |
Description |
| IPR000910 |
High mobility group, HMG1/HMG2 |
| IPR009071 |
High mobility group, superfamily |
| IPR013558 |
CTNNB1 binding, N-teminal |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:45934
Korinek V et al.,
"Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse."
Mol Cell Biol 1998 Mar;18(3):1248-56
(Latest)
J:152838
Fu H et al.,
"A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development."
J Neurosci 2009 Sep 9;29(36):11399-408
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All references(71)
|
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