Symbol
Name
ID
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Synonyms
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Wnt14b, Wnt15
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(19)
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Alleles
and
phenotypes
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All alleles(3) :
Targeted, knock-out(1)
Targeted, other(2)
| Homozygous null mice display neonatal lethality, disrupted ureteric bud branching, impaired Mullerian duct formation, and incompletely penetrant cleft lip and palate. In mice with alleles that decrease expression kidneys are smaller with fewer mature nephrons. |
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Polymorphisms
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All PCR and RFLP(4) :
PCR(2)
RFLP(2)
SNPs within 2kb(132 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (32 records)
Data Summary:
Assays (9)
Results (144)
Tissues (127)
Images (12)
Theiler Stages: 1,2,3,4,5,8,9,10,11,13,17,18,19,20,22,23,25,26,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
5 |
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43 |
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RNA in situ |
3 |
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99 |
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RNase protection |
1 |
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2 |
cDNA source data(10)
External Resources:
Allen Brain Atlas
GENSAT
GEO
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Molecular
reagents
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All nucleic(27)
Genomic(6)
cDNA(10)
Primer pair(8)
Other(3)
Microarray probesets(2)
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Other database
links
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Protein
domains
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| InterPro ID |
Description |
| IPR005816 |
Secreted growth factor Wnt protein |
| IPR005817 |
Wnt superfamily |
| IPR018161 |
Secreted growth factor Wnt protein, conserved site |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:45564
Bergstein I et al.,
"Isolation of two novel WNT genes, WNT14 and WNT15, one of which (WNT15) is closely linked to WNT3 on human chromosome 17q21"
Genomics 1997 Dec 15;46(3):450-8
(Latest)
J:153202
Gerber SD et al.,
"The murine Fgfrl1 receptor is essential for the development of the metanephric kidney."
Dev Biol 2009 Nov 1;335(1):106-19
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All references(47)
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