Symbol
Name
ID
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Synonyms
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clf, clf1, Wnt14b, Wnt15
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(19)
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Alleles
and
phenotypes
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All alleles(4) :
Targeted, knock-out(1)
Targeted, other(2)
Spontaneous(1)
| Homozygous null mice display neonatal lethality, disrupted ureteric bud branching, impaired Mullerian duct formation, and incompletely penetrant cleft lip and palate. In mice with alleles that decrease expression kidneys are smaller with fewer mature nephrons. |
Phenotype Images (1)
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Polymorphisms
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All PCR and RFLP(4) :
PCR(2)
RFLP(2)
SNPs within 2kb(132 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (34 records)
Data Summary:
Assays (10)
Results (152)
Tissues (133)
Images (20)
Theiler Stages: 1,2,3,4,5,8,9,10,11,13,15,17,18,19,20,21,22,23,25,26,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
5 |
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43 |
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RNA in situ |
4 |
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107 |
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RNase protection |
1 |
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2 |
cDNA source data(12)
External Resources:
Allen Brain Atlas
GENSAT
GEO
ArrayExpress
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Molecular
reagents
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All nucleic(30)
Genomic(6)
cDNA(12)
Primer pair(9)
Other(3)
Microarray probesets(2)
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Other database
links
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Protein
domains
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| InterPro ID |
Description |
| IPR005816 |
Secreted growth factor Wnt protein |
| IPR005817 |
Wnt superfamily |
| IPR018161 |
Secreted growth factor Wnt protein, conserved site |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:8487
Biddle FG et al.,
"Major gene determination of liability to spontaneous cleft lip in the mouse."
J Craniofac Genet Dev Biol Suppl 1986;2():67-88
(Latest)
J:154102
Cain JE et al.,
"GLI3 repressor controls nephron number via regulation of Wnt11 and Ret in ureteric tip cells."
PLoS One 2009;4(10):e7313
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All references(57)
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Other
accession IDs
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MGD-MRK-16443, MGD-MRK-2011, MGI:99658
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Analysis Tools
MGI BioMart
