Symbol
Name
ID
|
|
|
Synonyms
|
Ed1, Eda-A1, Eda-A2, EDA1
|
|
Genetic Map
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(48)
|
Alleles
and
phenotypes
|
All alleles(20) :
Spontaneous(14)
Chemically induced(2)
Radiation induced(4)
| Mutant hemizygous males and homozygous females have defects in ectodermal derivatives with absence of guard hairs, zigzags and tail hair, reduced eyelid opening, fewer vibrissae and defects of teeth and exocrine glands. Homozygous females are often sterile. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (2)
Phenotype Images (4)
|
|
Polymorphisms
|
SNPs within 2kb(803 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (19 records)
Data Summary:
Assays (12)
Results (107)
Tissues (68)
Images (53)
Theiler Stages: 7,8,10,11,16,17,18,19,20,21,22,23,24,25,26,28
| |
Assay Type |
Assays |
|
Results |
| |
Western blot |
2 |
|
4 |
| |
RT-PCR |
1 |
|
1 |
| |
RNA in situ |
7 |
|
94 |
| |
Northern blot |
2 |
|
8 |
cDNA source data(22)
External Resources:
Allen Brain Atlas
GEO
|
Molecular
reagents
|
All nucleic(41)
Genomic(13)
cDNA(24)
Primer pair(1)
Other(3)
Antibodies(1)
Microarray probesets(6)
|
Other database
links
|
| Ensembl Gene Model |
ENSMUSG00000059327 |
| DoTS |
DT.101713740, DT.111023308, DT.111023309, DT.111023327, DT.55281652, DT.91323351, DT.94242826, DT.94242835 |
| UniGene |
328086 |
| DFCI |
TC1587613, TC1596605, TC1597485, TC1599213 |
| NIA Mouse Gene Index |
U020049 |
| Entrez Gene |
13607 |
| VEGA Gene Model |
OTTMUSG00000018058 |
| International Mouse Knockout Project Status |
Eda |
|
Protein
domains
|
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:78116
Falconer DS et al.,
"The environment in relation to selection for size in mice"
J Genet 1952;51():67-80
(Latest)
J:152818
Melnick M et al.,
"Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm."
BMC Dev Biol 2009;9():32
|
All references(170)
|
Other
accession IDs
|
MGD-MRK-14700, MGI:98473
|
