Symbol
Name
ID
|
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Synonyms
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D18Wsu154e, Dia1, Drf1, p140mDia
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Genetic Map
|
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Sequence Map
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Mammalian
homology
|
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Sequences
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All sequences(35)
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Alleles
and
phenotypes
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All alleles(80) :
Targeted, knock-out(2)
Targeted, other(1)
Gene trapped(77)
| Mice homozygous for a null allele exhibit abnormal hematopoiesis, bone marrow cell morphology, spleen morphology, skin physiology, skull morphology, and postnatal growth. |
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Polymorphisms
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RFLP(1)
SNPs within 2kb(297 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
|
Literature Summary: (1 records)
Data Summary:
Assays (1)
Results (6)
Tissues (2)
Theiler Stages: 11
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
1 |
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6 |
cDNA source data(125)
External Resources:
Allen Brain Atlas
GEO
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Molecular
reagents
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All nucleic(129)
cDNA(128)
Primer pair(1)
Microarray probesets(3)
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Other database
links
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| Ensembl Gene Model |
ENSMUSG00000024456 |
| DoTS |
DT.101178148, DT.101359579, DT.101741147, DT.110785411, DT.488922 |
| UniGene |
195916 |
| PDB |
1V9D, 1Z2C, 2BAP, 2BNX, 2F31, 2V8F, 3EG5 |
| DFCI |
TC1576657, TC1626264, TC1641595 |
| NIA Mouse Gene Index |
U038352 |
| Entrez Gene |
13367 |
| VEGA Gene Model |
OTTMUSG00000021095 |
| International Mouse Knockout Project Status |
Diap1 |
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Protein
domains
|
Graphical View
of Protein Domain Structure
|
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References
|
(Earliest)
J:41124
Watanabe N et al.,
"p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin."
EMBO J 1997 Jun 2;16(11):3044-56
(Latest)
J:153615
DeWard AD et al.,
"Loss of RhoB expression enhances the myelodysplastic phenotype of mammalian diaphanous-related Formin mDia1 knockout mice."
PLoS One 2009;4(9):e7102
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All references(26)
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Other
accession IDs
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MGD-MRK-35685, MGI:107220
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