Symbol
Name
ID
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Pik3r2
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)
MGI:1098772
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Nomenclature History
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Synonyms
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p85beta
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Genetic Map
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Sequence Map
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Mammalian
homology
|
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Sequences
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All sequences(27)
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Alleles
and
phenotypes
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All alleles(3) :
Targeted, knock-out(1)
Targeted, other(2)
| Mice homozygous for disruptions in this gene have lower blood glucose levels both when fed and after fasting. Insulin sensitivity is improved as well. |
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Polymorphisms
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SNPs within 2kb(22 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
|
Literature Summary: (3 records)
Data Summary:
Assays (1)
Results (25)
Tissues (18)
Theiler Stages: 21,25,28
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Assay Type |
Assays |
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Results |
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Northern blot |
1 |
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25 |
cDNA source data(7)
External Resources:
Allen Brain Atlas
GEO
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Molecular
reagents
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All nucleic(7)
cDNA(7)
Microarray probesets(2)
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Other database
links
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Protein
domains
|
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:36742
Pons S et al.,
"The structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinase."
Mol Cell Biol 1995 Aug;15(8):4453-65
(Latest)
J:148122
Alcazar I et al.,
"p85beta phosphoinositide 3-kinase regulates CD28 coreceptor function."
Blood 2009 Apr 2;113(14):3198-208
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All references(29)
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