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Rhoa Gene Detail
 Symbol
Name
ID
Rhoa
ras homolog gene family, member A
MGI:1096342

Nomenclature History
Synonyms Arha, Arha1, Arha2, RhoA
Genetic Map
Chromosome 9
Syntenic
 
Mapping data( 4)
Sequence Map
Chr9:108208754-108239742 bp, + strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: small GTPase, Rho type
TreeFam: TF300837
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000007815 Ensembl Gene Model | MGI Sequence Detail 30989 C57BL/6J ± Kb
transcript NM_016802 RefSeq | MGI Sequence Detail 2126 C57BL/6
polypeptide Q9QUI0 UniProt | EBI | MGI Sequence Detail 193 Not Applicable
For the selected sequences
All sequences(30)
Alleles
and
phenotypes 		All alleles(195) : Gene trapped(195)
Polymorphisms PCR(1) SNPs within 2kb(37 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (31 annotations)
Process actin cytoskeleton organization, androgen receptor signaling pathway...
Component cytoplasm, cytoskeleton...
Function GTP binding, GTPase activity...
External Resources: FuncBase
Expression Literature Summary: (24 records)
Data Summary: Assays (11)    Results (29)    Tissues (15)    Images (18)
Theiler Stages: 15,18,19,20,21,22,23,24,25,26,28
  Assay Type Assays   Results
      Western blot 8   17
      RNA in situ 1   4
      Immunohistochemistry 2   8
cDNA source data(10)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(11) cDNA(10) Primer pair(1) Antibodies(4)
Microarray probesets(3)
Pathways
cyclic AMP biosynthesis
Other database
links
Ensembl Gene Model ENSMUSG00000007815
DoTS DT.101138346, DT.102545939, DT.94382596, DT.99840870
Consensus CDS Project CCDS23521.1
DFCI TC1573100
Entrez Gene 11848
International Mouse Knockout Project Status Rhoa
Protein
domains
InterPro ID Description
IPR001806 Ras GTPase
IPR003578 Small GTPase, Rho type
IPR005225 Small GTP-binding protein
IPR013753 Ras
Graphical View of Protein Domain Structure
References
(Earliest) J:87888 Ridley AJ et al., "The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors." Cell 1992 Aug 7;70(3):389-99
(Latest) J:148410 Combes AN et al., "Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development." Dev Dyn 2009 May;238(5):1033-41
All references(72)
Other
accession IDs 		MGI:1355308
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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