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Wnt8b Gene Detail
 Symbol
Name
ID
Wnt8b
wingless related MMTV integration site 8b
MGI:109485

Nomenclature History
Genetic Map
Chromosome 19
43.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 7)

Sequence Map
Chr19:44567963-44587007 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Wnt8b ± 2 cM)
Protein SuperFamily: int-1 transforming protein
TreeFam: TF105310
Sequences
Representative Sequences Length Strain/Species Flank
genomic 22423 NCBI Gene Model | MGI Sequence Detail 19045 C57BL/6J ± Kb
transcript NM_011720 RefSeq | MGI Sequence Detail 3376 C57BL/6
polypeptide Q9WUD6 UniProt | EBI | MGI Sequence Detail 350 Not Applicable
For the selected sequences
All sequences(17)
Alleles
and
phenotypes 		All alleles(1) : Targeted, knock-out(1)
Polymorphisms All PCR and RFLP(3) : PCR(1) RFLP(2) SNPs within 2kb(135 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cell-cell signaling, multicellular organismal development...
Component extracellular region, proteinaceous extracellular matrix...
Function receptor binding, signal transducer activity...
External Resources: FuncBase
Expression Literature Summary: (53 records)
Data Summary: Assays (12)    Results (177)    Tissues (156)    Images (22)
Theiler Stages: 4,5,8,9,11,13,15,17,19,20,21,22,23,26,28
  Assay Type Assays   Results
      RT-PCR 5   13
      RNA in situ 7   164
cDNA source data(17)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(31) cDNA(20) Primer pair(8) Other(3)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000036961
DoTS DT.486231
UniGene 88365
DFCI TC1587932
NIA Mouse Gene Index U019488
Entrez Gene 22423
International Mouse Knockout Project Status Wnt8b
Protein
domains
InterPro ID Description
IPR005816 Secreted growth factor Wnt protein
IPR005817 Wnt superfamily
IPR013301 Wnt-8 protein
IPR018161 Secreted growth factor Wnt protein, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:39203 Varlet I et al., "nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation." Development 1997 Mar;124(5):1033-44
(Latest) J:155332 Fotaki V et al., "Loss of Wnt8b has no overt effect on hippocampus development but leads to altered Wnt gene expression levels in dorsomedial telencephalon." Dev Dyn 2010 Jan;239(1):284-96
All references(61)
Other
accession IDs 		MGD-MRK-39484
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory