Symbol
Name
ID
|
|
|
Genetic Map
|
|
|
Sequence Map
|
|
Mammalian homology
|
|
|
Sequences
|
All sequences(21)
|
Alleles and phenotypes
|
All alleles(1) :
Targeted, knock-out(1)
| Mice homozygous for disruptions in this gene usually die by the end of the second day after birth. Those that do survive have reduced kidneys and abnormal steriocilia in the inner ear. |
|
|
Polymorphisms
|
SNPs within 2kb(900 from dbSNP Build 128)
|
Gene Ontology (GO) classifications
|
|
|
Expression
|
Literature Summary: (14 records)
Data Summary:
Assays (1)
Results (8)
Tissues (2)
Images (10)
Theiler Stages: 21
| |
Assay Type |
Assays |
|
Results |
| |
RNA in situ |
1 |
|
8 |
cDNA source data(47)
External Resources:
Allen Brain Atlas
GEO
|
Molecular reagents
|
All nucleic(50)
Genomic(2)
cDNA(47)
Other(1)
Microarray probesets(1)
|
Other database links
|
|
Protein domains
|
| InterPro ID |
Description |
| IPR000413 |
Integrin alpha chain |
| IPR013513 |
Integrin alpha chain, C-terminal, cytoplasmic region |
| IPR013517 |
FG-GAP |
| IPR013519 |
Integrin alpha beta-propellor |
| IPR013649 |
Integrin alpha-2 |
| IPR018184 |
Integrin alpha chain, C-terminal cytoplasmic region, conserved site |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:38838
Muller U et al.,
"Integrin alpha8beta1 is critically important for epithelial-mesenchymal interactions during kidney morphogenesis."
Cell 1997 Mar 7;88(5):603-13
(Latest)
J:152844
Driskell RR et al.,
"Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis."
Development 2009 Aug;136(16):2815-23
|
All references(18)
|
Other accession IDs
|
MGD-MRK-38487, MGI:2138946
|