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Pik3r3 Gene Detail
 Symbol
Name
ID
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
MGI:109277


Nomenclature History
Synonyms p55pik
Genetic Map
Chromosome 4
Syntenic
 
Mapping data( 2)
Sequence Map
Chr4:115894223-115975661 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: phosphatidylinositol 3-kinase, regulatory subunit, p85 type
TreeFam: TF102033
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000009411 VEGA Gene Model | MGI Sequence Detail 81439 C57BL/6J ± Kb
transcript NM_181585 RefSeq | MGI Sequence Detail 5004 C57BL/6
polypeptide Q64143 UniProt | EBI | MGI Sequence Detail 461 Not Applicable
For the selected sequences
All sequences(22)
Alleles
and
phenotypes
All alleles(11) : Gene trapped(11)
Polymorphisms SNPs within 2kb(185 from dbSNP Build 128)   SNPs within 2kb including multiple locations(187)
Gene Ontology
(GO)
classifications
All GO classifications(6)
Process insulin receptor signaling pathway
Component phosphoinositide 3-kinase complex
Function 1-phosphatidylinositol-3-kinase regulator activity, kinase activity...
External Resources: MouseFunc
Expression Literature Summary: (3 records)
Data Summary: Assays (2)    Results (33)    Tissues (19)
Theiler Stages: 21,25,28
  Assay Type Assays   Results
      Northern blot 2   33
cDNA source data(111)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(113) Genomic(1) cDNA(112)
Microarray probesets(1)
Other database
links
Ensembl Gene Model ENSMUSG00000028698
DoTS DT.488107
UniGene 253819
DFCI TC1598438, TC1601114
NIA Mouse Gene Index U042570
Entrez Gene 18710
VEGA Gene Model OTTMUSG00000009411
International Mouse Knockout Project Status Pik3r3
Protein
domains
InterPro ID Description
IPR000980 SH2 motif
IPR001720 PI3 kinase, P85 regulatory subunit
Graphical View of Protein Domain Structure
References
(Earliest) J:20946 Venkitaraman AR et al., "Interleukin-7 induces the association of phosphatidylinositol 3-kinase with the alpha chain of the interleukin-7 receptor." Eur J Immunol 1994 Sep;24(9):2168-74
(Latest) J:129381 Eickholt BJ et al., "Control of Axonal Growth and Regeneration of Sensory Neurons by the p110delta PI 3-Kinase." PLoS ONE 2007;2(9):e869
All references(7)
Other
accession IDs
MGD-MRK-38322, MGI:2140152

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory