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Fzd7 Gene Detail
 Symbol
Name
ID
Fzd7
frizzled homolog 7 (Drosophila)
MGI:108570

Nomenclature History
Synonyms Fz7
Genetic Map
Chromosome 1
30.1 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 2)

Sequence Map
Chr1:59539268-59543803 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Fzd7 ± 2 cM)
Protein SuperFamily: G protein-coupled receptor frizzled
TreeFam: TF317907
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000020777 VEGA Gene Model | MGI Sequence Detail 4536 C57BL/6J ± Kb
transcript NM_008057 RefSeq | MGI Sequence Detail 4840 C57BL/6
polypeptide Q61090 UniProt | EBI | MGI Sequence Detail 572 Not Applicable
For the selected sequences
All sequences(20)
Alleles
and
phenotypes 		All alleles(4) : Gene trapped(4)
Polymorphisms RFLP(1) SNPs within 2kb(24 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(13)
Process cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway...
Component integral to membrane, membrane...
Function G-protein coupled receptor activity, non-G-protein coupled 7TM receptor activity...
External Resources: MouseFunc
Expression Literature Summary: (27 records)
Data Summary: Assays (8)    Results (135)    Tissues (123)    Images (20)
Theiler Stages: 1,2,3,4,5,17,18,19,20,22,23,24,28
  Assay Type Assays   Results
      RT-PCR 6   28
      RNA in situ 2   107
cDNA source data(62)
External Resources: Allen Brain Atlas  GENSAT  GEO 
Molecular
reagents 		All nucleic(71) Genomic(1) cDNA(63) Primer pair(6) Other(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000041075
DoTS DT.101212726, DT.523781
UniGene 297906
DFCI TC1577715
NIA Mouse Gene Index U000317
Entrez Gene 14369
VEGA Gene Model OTTMUSG00000020777
International Mouse Knockout Project Status Fzd7
Protein
domains
InterPro ID Description
IPR000024 Frizzled cysteine-rich domain
IPR000539 Frizzled protein
IPR015526 Frizzled related
IPR017981 GPCR, family 2-like
IPR020067 Frizzled-like domain
IPR020068 Frizzled domain, subgroup
Graphical View of Protein Domain Structure
References
(Earliest) J:37068 Wang Y et al., "A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled." J Biol Chem 1996 Feb 23;271(8):4468-76
(Latest) J:152099 Bi Y et al., "Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells." J Cell Biochem 2009 Jun 26;108(1):295-303
All references(33)
Other
accession IDs 		MGD-MRK-37614
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
11/20/2009
MGI_4.31
Web browser compatibility 		The Jackson Laboratory