Symbol
Name
ID
|
|
|
STS
|
D10Mit24
|
|
Synonyms
|
Ifg, IFN-gamma
|
|
Genetic Map
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(22)
|
Alleles
and
phenotypes
|
All alleles(5) :
Targeted, knock-out(2)
Targeted, other(3)
| Mutants show immune system abnormalities including decreased inflammatory response in one line, and uncontrolled splenocyte proliferation and susceptibility to intracellular pathogens in another. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (1)
|
|
Polymorphisms
|
All PCR and RFLP(9) :
PCR(1)
RFLP(8)
SNPs within 2kb(29 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (12 records)
Data Summary:
Assays (6)
Results (82)
Tissues (45)
Images (3)
Theiler Stages: 16,18,20,21,22,23,24,25,26,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
5 |
|
79 |
| |
Northern blot |
1 |
|
3 |
cDNA source data(13)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(22)
cDNA(14)
Primer pair(5)
Other(3)
Microarray probesets(2)
|
Other database
links
|
|
Protein
domains
|
| InterPro ID |
Description |
| IPR002069 |
Interferon gamma |
| IPR009079 |
Four-helical cytokine-like, core |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:19935
Gray PW et al.,
"Cloning and expression of murine immune interferon cDNA."
Proc Natl Acad Sci U S A 1983 Oct;80(19):5842-6
(Latest)
J:155738
Gu T et al.,
"Central role of IFNgamma-indoleamine 2,3-dioxygenase axis in regulation of interleukin-12-mediated antitumor immunity."
Cancer Res 2010 Jan 1;70(1):129-38
|
All references(1036)
|
Other
accession IDs
|
MGD-MRK-11214, MGD-MRK-36231
|
Analysis Tools
MGI BioMart
