Symbol
Name
ID
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Synonyms
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branched chain alpha-keto acid dehydrogenase complex subunit E3, dihydrolipoyl dehydrogenase
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(31)
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Alleles
and
phenotypes
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All alleles(2) :
Targeted, knock-out(1)
Gene trapped(1)
| Embryos homozygous for a targeted null mutation exhibit a developmental delay at 7.5 days postcoitum and are resorbed by 9.5 days postcoitum. |
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Polymorphisms
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PCR(1)
SNPs within 2kb(98 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (2 records)
Data Summary:
Assays (2)
Results (119)
Tissues (98)
Images (16)
Theiler Stages: 22
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Assay Type |
Assays |
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Results |
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RNA in situ |
2 |
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119 |
cDNA source data(15)
External Resources:
Allen Brain Atlas
GEO
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Molecular
reagents
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All nucleic(22)
Genomic(3)
cDNA(17)
Primer pair(1)
Other(1)
Microarray probesets(2)
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Pathways
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Other database
links
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Protein
domains
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| InterPro ID |
Description |
| IPR000815 |
Mercuric reductase |
| IPR001327 |
Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region |
| IPR004099 |
Pyridine nucleotide-disulphide oxidoreductase, dimerisation |
| IPR006258 |
Dihydrolipoamide dehydrogenase |
| IPR012999 |
Pyridine nucleotide-disulphide oxidoreductase, class I, active site |
| IPR013027 |
FAD-dependent pyridine nucleotide-disulphide oxidoreductase |
| IPR016156 |
FAD/NAD-linked reductase, dimerisation |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:34474
Lyu MS et al.,
"Genetic mapping of the human and mouse phospholipase C genes."
Mamm Genome 1996 Jul;7(7):501-4
(Latest)
J:151002
Pagliarini DJ et al.,
"A mitochondrial protein compendium elucidates complex I disease biology."
Cell 2008 Jul 11;134(1):112-23
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All references(17)
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Other
accession IDs
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MGD-MRK-35921, MGI:2144786, MGI:2144881
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