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Fosl1 Gene Detail
 Symbol
Name
ID
Fosl1
fos-like antigen 1
MGI:107179

Nomenclature History
Synonyms fra-1, Fra1
Genetic Map
Chromosome 19
0.5 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 7)

Sequence Map
Chr19:5447698-5455938 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Fosl1 ± 2 cM)
Protein SuperFamily: fos transforming protein
TreeFam: TF326301
Sequences
Representative Sequences Length Strain/Species Flank
genomic 14283 NCBI Gene Model | MGI Sequence Detail 8241 C57BL/6J ± Kb
transcript NM_010235 RefSeq | MGI Sequence Detail 1705 C57BL/6
polypeptide P48755 UniProt | EBI | MGI Sequence Detail 273 Not Applicable
For the selected sequences
All sequences(19)
Alleles
and
phenotypes 		All alleles(4) : Targeted, other(3) Gene trapped(1)
Polymorphisms PCR(1) SNPs within 2kb(66 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process cellular response to extracellular stimulus, regulation of transcription, DNA-dependent...
Component nucleus
Function DNA binding, protein dimerization activity...
External Resources: FuncBase
Expression Literature Summary: (4 records)
Data Summary: Assays (1)    Results (7)    Tissues (5)    Images (1)
Theiler Stages: 16,19,20,21,28
  Assay Type Assays   Results
      RT-PCR 1   7
cDNA source data(20)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(24) Genomic(1) cDNA(20) Primer pair(3)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000024912
DoTS DT.40173429
Consensus CDS Project CCDS29464.1
UniGene 6215
DFCI TC1580200
NIA Mouse Gene Index U038721
Entrez Gene 14283
International Mouse Knockout Project Status Fosl1
Protein
domains
InterPro ID Description
IPR000837 Fos transforming protein
IPR004827 Basic-leucine zipper (bZIP) transcription factor
IPR011616 bZIP transcription factor, bZIP-1
Graphical View of Protein Domain Structure
References
(Earliest) J:33399 Jeske YW et al., "Analysis of the role of Amh and Fra1 in the Sry regulatory pathway." Mol Reprod Dev 1996 Jun;44(2):153-8
(Latest) J:147099 Morishita H et al., "Fra-1 negatively regulates lipopolysaccharide-mediated inflammatory responses." Int Immunol 2009 Apr;21(4):457-65
All references(19)
Other
accession IDs 		MGD-MRK-35640, MGI:2147739
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory