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Tagln Gene Detail
 Symbol
Name
ID
Tagln
transgelin
MGI:106012


Nomenclature History
Synonyms SM-22 alpha, SM22, Sm22a
Genetic Map
Chromosome 9
27.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 2)

Sequence Map
Chr9:45737711-45743981 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Tagln ± 2 cM)
Protein SuperFamily: smooth muscle protein SM22
TreeFam: TF313921
Sequences
Representative Sequences Length Strain/Species Flank
genomic 21345 NCBI Gene Model | MGI Sequence Detail 6271 C57BL/6J ± Kb
transcript NM_011526 RefSeq | MGI Sequence Detail 1426 C57BL/6
polypeptide P37804 UniProt | EBI | MGI Sequence Detail 201 Not Applicable
For the selected sequences
All sequences(20)
Alleles
and
phenotypes
All alleles(5) : Targeted, other(5)
Polymorphisms SNPs within 2kb(38 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(3)
Process muscle organ development
Component cytoplasm
External Resources: MouseFunc
Expression Literature Summary: (44 records)
Data Summary: Assays (3)    Results (16)    Tissues (16)    Images (2)
Theiler Stages: 19,20,21,22,23,28
  Assay Type Assays   Results
      Western blot 1   6
      RT-PCR 1   9
      RNA in situ 1   1
cDNA source data(11)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(16) Genomic(3) cDNA(11) Primer pair(2) Antibodies(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000032085
PDB 1UJO
DFCI TC1574670, TC1602295
NIA Mouse Gene Index U030804
Entrez Gene 21345
International Mouse Knockout Project Status Tagln
Protein
domains
InterPro ID Description
IPR000557 Calponin repeat
IPR001061 Transgelin (SM22-alpha)
IPR001715 Calponin-like actin-binding
IPR003096 SM22/calponin
Graphical View of Protein Domain Structure
References
(Earliest) J:35896 Almendral JM et al., "Expression, cloning and cDNA sequence of a fibroblast serum-regulated gene encoding a putative actin-associated protein (p27)." Exp Cell Res 1989 Apr;181(2):518-30
(Latest) J:152906 Xie J et al., "Endothelial-specific expression of WNK1 kinase is essential for angiogenesis and heart development in mice." Am J Pathol 2009 Sep;175(3):1315-27
All references(76)
Other
accession IDs
MGD-MRK-33694

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
Web browser compatibility
The Jackson Laboratory