Symbol
Name
ID
|
|
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Synonyms
|
2410016A19Rik, PKB, PKBbeta
|
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Genetic Map
|
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Sequence Map
|
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Mammalian
homology
|
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Sequences
|
All sequences(43)
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Alleles
and
phenotypes
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All alleles(39) :
Targeted, knock-out(3)
Targeted, other(3)
Gene trapped(33)
| Homozygotes for targeted null mutations exhibit insulin resistance and elevated plasma triglycerides. In males, the insulin resistance may progress to overt diabetes. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (1)
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Polymorphisms
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RFLP(2)
SNPs within 2kb(192 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
|
|
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Expression
|
Literature Summary: (15 records)
Data Summary:
Assays (1)
Results (11)
Tissues (11)
Theiler Stages: 28
| |
Assay Type |
Assays |
|
Results |
| |
Western blot |
1 |
|
11 |
cDNA source data(130)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
|
All nucleic(132)
Genomic(1)
cDNA(131)
Antibodies(2)
Microarray probesets(4)
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Other database
links
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Protein
domains
|
Graphical View
of Protein Domain Structure
|
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References
|
(Earliest)
J:32638
Staal SP,
"Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma."
Proc Natl Acad Sci U S A 1987 Jul;84(14):5034-7
(Latest)
J:152016
Di Lorenzo A et al.,
"Akt1 is critical for acute inflammation and histamine-mediated vascular leakage."
Proc Natl Acad Sci U S A 2009 Aug 25;106(34):14552-7
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All references(61)
|
Other
accession IDs
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MGD-MRK-28173, MGI:1923730, MGI:2142261
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