Symbol
Name
ID
|
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Synonyms
|
D11Bhm185e, Hfh11, whn
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Genetic Map
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Sequence Map
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Mammalian
homology
|
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Sequences
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All sequences(22)
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Alleles
and
phenotypes
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All alleles(16) :
Targeted, knock-out(1)
Targeted, other(5)
Gene trapped(4)
Spontaneous(6)
| Homozygotes for different mutations have in genetically determined absence or loss of hair and failed hair keratinization, premature lethality (differing by genetic background) and absence of thymus, resulting in multiple immune abnormalities. Heterozygotes have enlarged thymuses. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (3)
Phenotype Images (4)
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Polymorphisms
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PCR(3)
SNPs within 2kb(18 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
|
Literature Summary: (27 records)
Data Summary:
Assays (12)
Results (67)
Tissues (35)
Images (13)
Theiler Stages: 12,14,16,18,19,20,21,22,23,24,25,26,28
| |
Assay Type |
Assays |
|
Results |
| |
Western blot |
1 |
|
6 |
| |
RT-PCR |
4 |
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31 |
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RNA in situ |
4 |
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18 |
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Immunohistochemistry |
2 |
|
10 |
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Northern blot |
1 |
|
2 |
cDNA source data(8)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
|
All nucleic(33)
Genomic(18)
cDNA(8)
Primer pair(5)
Other(2)
Antibodies(1)
Microarray probesets(2)
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Other database
links
|
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Protein
domains
|
| InterPro ID |
Description |
| IPR001766 |
Transcription factor, fork head |
| IPR011991 |
Winged helix repressor DNA-binding |
| IPR018122 |
Transcription factor, fork head, conserved site |
Graphical View
of Protein Domain Structure
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References
|
(Earliest)
J:2484
Truslove GM,
"Genetical studies on the skeleton of the mouse. V. 'Interfrontal' and 'parted frontals'"
J Genet 1952;51():115-122
(Latest)
J:154156
Bressenot A et al.,
"Assessment of apoptosis by immunohistochemistry to active caspase-3, active caspase-7, or cleaved PARP in monolayer cells and spheroid and subcutaneous xenografts of human carcinoma."
J Histochem Cytochem 2009 Apr;57(4):289-300
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All references(340)
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Other
accession IDs
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MGD-MRK-12946, MGD-MRK-23783, MGD-MRK-35270, MGI:106810
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