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Ctrb1 Gene Detail
 Symbol
Name
ID
Ctrb1
chymotrypsinogen B1
MGI:88559
Synonyms 2200008D09Rik, Prt-2
Genetic Map
Chromosome 8
57.98 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 15)

Sequence Map
Chr8:114210421-114214910 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Ctrb1 ± 2 cM)
Protein SuperFamily: trypsin
TreeFam: TF330455
Sequences
Representative Sequences Length Strain/Species Flank
genomic 66473 NCBI Gene Model | MGI Sequence Detail 4490 C57BL/6J ± Kb
transcript NM_025583 RefSeq | MGI Sequence Detail 887 C57BL/6
polypeptide Q9CR35 UniProt | EBI | MGI Sequence Detail 263 Not Applicable
For the selected sequences
All sequences(27) RefSeq(2) UniProt(1)
Alleles
and
phenotypes
All alleles(8) : Targeted, other(2) Gene trapped(6)
Polymorphisms RFLP(2) SNPs within 2kb(47 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process digestion, positive regulation of apoptosis...
Component cytoplasm, extracellular region...
Function catalytic activity, hydrolase activity...
External Resources: FuncBase
Expression Literature Summary: (4 records)
Data Summary: Assays (2)    Results (5)    Tissues (2)    Images (3)
Theiler Stages: 20,22
  Assay Type Assays   Results
      RT-PCR 1   3
      RNA in situ 1   2
cDNA source data(2135)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents
All nucleic(2137) cDNA(2136) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000031957 (Evidence)
Entrez Gene 66473 (Evidence)
UniGene 34374
DFCI TC1573641
DoTS DT.102540027, DT.94232982, DT.94233035, DT.97393043, DT.99871581
NIA Mouse Gene Index U030268
EC 3.4.21.1
Consensus CDS Project CCDS22679.1
International Mouse Knockout Project Status Ctrb1
Protein-related
information
Resource ID Description
InterPro IPR001254 Peptidase S1/S6, chymotrypsin/Hap
InterPro IPR001314 Peptidase S1A, chymotrypsin
InterPro IPR009003 Serine/cysteine peptidase, trypsin-like
InterPro IPR018114 Peptidase S1/S6, chymotrypsin/Hap, active site
Protein Ontology PRO:000006018 chymotrypsinogen B
Graphical View of Protein Domain Structure
References
(Earliest) J:5539 Watanabe T et al., "Genetic study of pancreatic proteinase and alpha-amylase in mice (Mus musculus)." Biochem Genet 1974 Nov;12(5):419-28
(Latest) J:139177 Hoffman BG et al., "Identification of transcripts with enriched expression in the developing and adult pancreas." Genome Biol 2008;9(6):R99
All references(21)
Other
accession IDs
MGD-MRK-13634, MGD-MRK-2243, MGI:1913723, MGI:2138990

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
09/02/2010
MGI_4.35
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