Symbol
Name
ID
|
Pscr2
corneal resistance to P. aeruginosa 2
MGI:97785
|
|
|
Synonyms
|
Pscr-2
|
|
Genetic Map
|
|
Chromosome 1
|
cM position of peak correlated region/marker: Syntenic
|
|
|
|
Mapping data(
1)
|
|
|
Alleles
and
phenotypes
|
All alleles(3) :
QTL(3)
| Mice resistant to corneal infection by P. aeruginosa have local infections that heal in 3-4 weeks. Infected susceptible mice show necrosis, eye shrinkage and blindness in 12-14 days. Dominant alleles at 2 genes are required for resistance. C57BL/6 has the dominant allele at Pscr1; BALB/c at Pscr2. |
|
Other database
links
|
|
|
References
|
(Earliest)
J:6633
Berk RS et al.,
"Genetic studies of the murine corneal response to Pseudomonas aeruginosa."
Infect Immun 1981 Oct;34(1):1-5
(Latest)
J:8914
Berk RS et al.,
"Genetic studies on resistant and susceptibility genes controlling the mouse cornea to infection with Pseudomonas aeruginosa."
Antibiot Chemother 1987;39():83-91
|
All references(3)
|
Other
accession IDs
|
MGD-MRK-13647, MGD-MRK-13649
|
Analysis Tools
MGI BioMart