MGI_4.01 - Phenotypes, Alleles & Disease Models

Phenotypes, Alleles & Disease Models
The Phenotypes/Alleles project in MGI enables access to spontaneous, induced, and genetically-engineered mutations and their strain-specific phenotypes.

Homozygote for the Ednrb^s mutation, originally
known as piebald spotting.

Access Data

Search for mutations or QTL based on phenotype, human disease, mutation type, gene, or genome location.: Phenotypes, Alleles & Disease Models Query
Search for a phenotype term to find relevant mutant genotypes.: Mammalian Phenotype (MP) Browser
Search for a human disease term to find mouse models.: Human Disease (OMIM) Browser
Search for candidate genes for a given phenotype within a genomic interval.: Genes & Markers Query
Input a list of genes and retrieve associated alleles and phenotypes.: Batch Query
Submit a new allele, mutation, or transgene and receive official nomenclature and an MGI accession identifier.: Allele Nomenclature Form
Describe characteristics of spontaneous, induced, or genetically engineered mutations already entered in MGI: Phenotype Data Submission Form
View guides to proper naming of alleles and mutations.: Quick Guide to Allele Nomenclature; Complete Guide to Nomenclature

FAQs

How do I...: .. find mutations in a specific gene? FAQ; .. find mouse models for a human disease or condition? FAQ; .. find mutations that cause a specific combination of phenotypes? FAQ; .. find all of one kind of allele (e.g. cre transgenes, LoxP/Frt-flanked alleles, etc.)? FAQ

More FAQs

Phenotypes, Alleles & Disease Models Includes

15 Apr 2008

18,821: Mutant alleles
7,374: Genes with mutant alleles
23,079: Genotypes with phenotype annotations
826: Human diseases with genotypic mouse models

More...

MGI_4.01 - Phenotypes, Alleles & Disease Models: Other Links

Download phenotype data reports
Mouse Nomenclature Home Page

Knockout Mice

NIH Knockout Mouse Project (KOMP) Data Coordination Center
European Conditional Mouse Mutagenesis Program (EUCOMM)
North American Conditional Mouse Mutagenesis project (NORCOMM)
Trans-NIH Knockout Mouse Initiatives
List of Deltagen and Lexicon Knock Out Mice available through repositories
List of knockout alleles in MGI

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support.	last database update 05/08/2008 MGI_4.01 Web browser compatibility