Phenotype Images

About This Image

The image shown here is of a two littermate mice where the right is homozygous for the spontaneous "obese" allele of leptin ( Lepob /Lepob).
Leptin is a hormone which regulates body fat as well as the sensation of hunger, and mice with homozygous loss-of-function alleles are hyperphagic, obese, and susceptible to diabetes and other complications.

Phenotype Images in MGI

Whenever possible the text annotations of phenotypes in MGI are complemented by images illustrating the phenotype (photographs, histology, x-rays, etc.). Images may be found on the relevant allele detail page(s). Phenotype images come either from journal articles (with permission of the journal) or through contributed submissions.