The Gene Expression Database (GXD) is a community resource for gene expression information from the laboratory mouse. GXD stores and integrates different types of expression data and makes these data freely available in formats appropriate for comprehensive analysis. There is particular emphasis on endogenous gene expression during mouse development. The project is funded by NIH/NICHD grant HD062499.
This page provides information about:
New expression data are made available on a weekly basis. These data are acquired from the literature by our curatorial staff and via electronic submission. GXD encourages researchers to submit their expression data to us. Data submission both increases the exposure of the work and the amount of data available to the scientific community. Guidelines for submitting data can be found here.
To facilitate electronic submission of expression data, we have developed the Gene Expression Notebook (GEN). Implemented in Microsoft® Excel, the GEN is easy to use and to customize as a laboratory notebook for storing and organizing expression data. Data can then be exported effortlessly for electronic submission to GXD. Researchers interested in obtaining the GEN and its user guide may download them here.
The Adult Mouse Anatomy (MA) ontology has been developed and continues to be refined to provide standardized nomenclature for annotating expression and phenotype data for the adult mouse. The MA organizes anatomical structures for the postnatal mouse spatially and functionally. You can use the browser to view anatomical terms and their relationships in a hierarchical display. We welcome your input. Please contact us with suggestions, additions, or questions about the MA.
Smith CM, Finger JH, Kadin JA, Richardson JE, Ringwald M. The gene expression database for mouse development (GXD): Putting developmental expression information at your fingertips. 2014. Dev Dyn Oct;243(10):1176-1186. PubMed
Smith CM, Finger JH, Hayamizu TF, McCright IJ, Xu J, Berghout J, Campbell J, Corbani LE, Forthofer KL, Frost PJ, Miers D, Shaw DR, Stone KR, Eppig JT, Kadin JA, Richardson JE, Ringwald M. The mouse Gene Expression Database (GXD): 2014 update. Nucleic Acids Res. 2014 Jan 1;42(D1):D818-D824. NAR PubMed
Hayamizu TF, Wicks MN, Davidson DR, Burger A, Ringwald M, Baldock RA. EMAP/EMAPA ontology of mouse developmental anatomy: 2013 update. J Biomed Semantics. 2013 Aug 26;4(1):15. PubMed
Ringwald M, Wu C, Su AI. BioGPS and GXD: mouse gene expression data-the benefits and challenges of data integration. Mamm Genome. 2012 Oct;23(9-10):550-8. PubMed
Finger JH, Smith CM, Hayamizu TF, McCright IJ, Eppig JT, Kadin JA, Richardson JE, Ringwald M. The mouse Gene Expression Database (GXD): 2011 update. Nucleic Acids Res 39(suppl 1): D835-D841. NAR PubMed
Smith CM, Finger JH, Hayamizu TF, McCright IJ, Eppig JT, Kadin JA, Richardson JE, Ringwald, M. The mouse Gene Expression Database (GXD): 2007 update. Nucleic Acids Res 2007 35(Database issue):D618-D623. NAR PubMed
Hayamizu TF, Mangan M, Corradi JP, Kadin JA, Ringwald M. The Adult Mouse Anatomical Dictionary: a tool for annotating and integrating data. Genome Biol, 2005;6:R29 PubMed.
Hill DP, Begley DA, Finger JH, Hayamizu TF, McCright IJ, Smith CM, Beal JS, Corbani LE, Blake JA, Eppig JT, Kadin JA, Richardson JE, Ringwald M. The Mouse Gene Expression Database (GXD): updates and enhancements. Nucleic Acids Res 2004; 32:D568-D571. NAR PubMed
Begley DA, Ringwald M. 2002. Electronic tools to manage gene expression data. Trends Genet 18:108-110.
Ringwald M, Eppig JT, Begley DA, Corradi JP, McCright IJ, Hayamizu TF, Hill DP, Kadin JA, Richardson JE. 2001. The Mouse Gene Expression Database (GXD). Nucleic Acids Res 29:98-101. PubMed
Ringwald M, Eppig JT, Richardson JE. 2000. GXD: integrated access to gene expression data for the laboratory mouse. Trends Genet 16:188-190. PubMed
Bard JBL, Kaufman MH, Dubreuil C, Brune RM, Burger A, Baldock RA and Davidson DR. 1998. An internet-accessible database of mouse developmental anatomy based on a systematic nomenclature. Mech Dev 74:111-120.
Ringwald M, Baldock R, Bard J, Kaufmann M, Eppig JT, Richardson JE, Nadeau JH, Davidson D. 1994. A database for mouse development. Science 265: 2033-2034. PubMed
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update