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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Pyy
peptide YY
MGI:99924
42 phenotypes from 6 alleles in 6 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sortm1(Pyy)Paba
involves: 129S4/SvJae
abnormal bone mineralization J:189512
abnormal bone structure J:189512
abnormal osteoclast morphology J:189512
decreased bone mineral density of femur J:189512
decreased bone strength J:189512
decreased compact bone area J:189512
decreased lean body mass J:189512
decreased trabecular bone volume J:189512
increased osteoclast cell number J:189512
short femur J:189512
small vertebrae J:189512
Pyytm1(cre)Hhzg/Pyytm1(cre)Hhzg
involves: 129
abnormal body weight J:111480
abnormal bone mineralization J:189512
abnormal bone structure J:189512
abnormal hypothalamus physiology J:111480
abnormal lumbar vertebrae morphology J:189512
normal behavior/neurological phenotype J:111480
decreased total body fat amount J:111480
impaired glucose tolerance J:111480
increased body weight J:111480
increased bone mineral content J:189512
increased bone mineral density J:189512
increased bone mineral density of lumbar vertebrae J:189512
increased circulating insulin level J:111480
increased circulating insulin-like growth factor I level J:111480
increased circulating testosterone level J:111480
increased gonadal fat pad weight J:111480
increased lean body mass J:111480
increased susceptibility to age related obesity J:111480
increased total body fat amount J:111480
increased trabecular bone volume J:189512
increased white adipose tissue amount J:111480
Pyytm1.1Batt/Pyytm1.1Batt
involves: C57BL/6 * FVB/N * SJL
abnormal adipose tissue distribution J:129742
abnormal response/metabolism to endogenous compounds J:129742
increased circulating leptin level J:129742
increased total body fat amount J:129742
obese J:129742
polyphagia J:129742
Pyytm1Able/Pyytm1Able
involves: 129S6/SvEvTac * C57BL/6 * FVB/N
no abnormal phenotype detected J:98886
Pyytm1Batt/Pyytm1Batt
involves: C57BL/6 * SJL
no abnormal phenotype detected J:129742
Pyytm1Mws/Pyytm1Mws
involves: C57BL/6J
abnormal lumbar vertebrae morphology J:130105
normal behavior/neurological phenotype J:130105
decreased bone mass J:130105
decreased bone mineral content J:130105
decreased bone mineral density J:130105
decreased lean body mass J:130105
normal growth/size/body region phenotype J:130105
increased percent body fat/body weight J:130105
increased susceptibility to weight gain J:130105

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory