Mst1r Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mst1r
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
MGI:99614

21 phenotypes from 6 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Foxa1^tm1(cre)Sew/Foxa1⁺ Mst1r^tm1Sew/Mst1r^tm1Sew involves: 129P2/OlaHsd * CD-1 * NIH Black Swiss	decreased susceptibility to bacterial infection	J:105979
Mst1r^Fv2-s/Mst1r^Fv2-s B6.DDD-Mst1r^Fv2-s	enlarged spleen	J:5120
Mst1r^Fv2-s/Mst1r^Fv2-s B6.DDD-Mst1r^Fv2-s	increased susceptibility to Retroviridae infection	J:5120
Mst1r^Fv2-s/Mst1r^Fv2-s C3H/Crgl	increased susceptibility to Retroviridae infection	J:167666
Mst1r^Fv2-s/Mst1r^Fv2-s either: A/Crgl or C57BL/Crgl	decreased susceptibility to Retroviridae infection	J:167666
Mst1r^Fv2-s/Mst1r^Fv2-s either: BALB/cCrgl or DBA/2Crgl or Swiss	enlarged spleen	J:167666
	increased susceptibility to Retroviridae infection	J:167666
Mst1r^tm1.1Sew/Mst1r^tm1.1Sew involves: 129/Ola * CD-1 * NIH Black Swiss	abnormal macrophage physiology	J:75503
	abnormal ovary morphology	J:75503
	abnormal type IV hypersensitivity reaction	J:75503
	decreased superovulation rate	J:85748
	increased acute inflammation	J:75503
	increased susceptibility to endotoxin shock	J:75503
	small ovary	J:75503
Mst1r^tm1Ber/Mst1r^tm1Ber involves: 129S1/Sv * 129X1/SvJ * CD-1	abnormal macrophage physiology	J:76451
	abnormal type IV hypersensitivity reaction	J:76451
	normal immune system phenotype	J:76451
	increased inflammatory response	J:76451
	increased susceptibility to bacterial infection	J:76451
Mst1r^tm1Sjd/Mst1r⁺ either: (involves: 129 * C57BL/6) or (involves: 129 * CD-1) or (involves: 129 * NIH Black Swiss)	abnormal macrophage physiology	J:54903
	increased susceptibility to bacterial infection	J:54903
Mst1r^tm1Sjd/Mst1r^tm1Sjd either: (involves: 129 * C57BL/6) or (involves: 129 * CD-1) or (involves: 129 * NIH Black Swiss)	embryonic lethality between implantation and somite formation, complete penetrance	J:54903
Mst1r^{tm2(Mst1r)Sew}/Mst1r^{tm2(Mst1r)Sew} FVB.129P2(Cg)-Mst1r^{tm2(Mst1r*)Sew}	hepatic necrosis	J:215969
	increased circulating alanine transaminase level	J:215969
	increased circulating interferon-gamma level	J:215969
	increased interferon-gamma secretion	J:215969
	increased susceptibility to xenobiotic induced morbidity/mortality	J:215969
Mst1r^{tm2(Mst1r)Sew}/Mst1r^{tm2(Mst1r)Sew} involves: 129P2/OlaHsd * Black Swiss * FVB/N	decreased spleen weight	J:215969
	increased susceptibility to Retroviridae infection	J:215969

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